Pathogenesis
This is the most common bacterial neurologic disease in ruminants.
What is Listeriosis?
Only possible using brain tissue or aborted placenta/fetus for bacterial isolation.
What is definitive diagnosis?
Cranial nerves V, VII, IX, X, and XII.
What are the cranial nerves affected by Listeriosis?
Penicilin
What is the drug of choice for treating Listeriosis?
Outbreaks of Listeriosis in humans have been traced to this food group, along with celery and cantaloupe.
What are dairy products?
The bacteria that causes Listeriosis.
What is Listeria monocytogenes?
This biochemical abnormality is caused by chronic salivary loss.
What is metabolic acidosis?
A deficit of this nerve causes head tilt, drooping ear, unilateral loss of facial sensation, and weak jaw tone.
What is the trigeminal nerve (CN V)?
Penicillin, ceftiofur, oxytetracycline, erythromycin, and trimethoprim/sulfonamide.
What drugs are Listeria monocytogenes susceptible to in vitro?
Listeria has been shown to survive certain methods of this process which is intended to eliminate pathogens.
What is pasteurization?
The primary clinical signs of Listeriosis.
What are silage eye (uveitis) and unilateral cranial nerve deficits?
These cerebrospinal fluid abnormalities are supportive of a Listeriosis diagnosis.
What are mononuclear pleocytosis and elevated protein?
A deficit of this nerve causes a unilateral loss of the menace response and loss of motor function to facial muscles.
What is the facial nerve (CN VII)?
Initiate with potassium penicillin IV and followed with procaine penicillin IM.
An organism that makes ATP by aerobic respiration if oxygen is present, but is capable of switching to fermentation if oxygen is absent.
What is a facultative anaerobe?
Environment, silage, and the feces of asymptomatic carriers.
What are the methods of transmission for Listeriosis?
This lesion found via histopathology supports a diagnosis of Listeriosis.
What is multifocal brainstem abscessation?
A deficit of this nerve causes unilaterally decreased tongue tone.
What is the glossopharyngeal nerve (CN IX)?
These clinical signs indicate a lower survival rate.
What are recumbency, excitement, and a weak or absent menace reflex?
Listeria monocytogenes was first described by this man in 1924 based on an outbreak of sudden death in rabbits.
Who is E.D.G Murray?
The intestinal wall, medulla oblongata, and placenta.
What are the most common sites of localization of Listeria?
This method of diagnosis is used on formalin fixed brainstem tissue to make a definitive diagnosis of Listeriosis.
A deficit of this cranial nerve leads to bloat.
What is the vagus nerve (CN X)?
High doses of antibiotics are required to treat Listeriosis in order to ensure minimal bactericidal concentration in this organ.
What is the brain?
Listeria monocytogenes is being investigated as an immunotherapy for several types of this disease.
What is cancer?