Pregnancy/Lactation
This trimester is the most vulnerable to teratogenic medication for a fetus.
What is First trimester
The two organs most impacted by getting older.
What are liver and kidneys?
Pediatric drug doses are often calculated based on these this patient-specific factor to account for developmental differences.
What is weight?
This form of estrogen is commonly used in feminizing hormone therapy for transgender women.
What is estradiol (estrogen)?
Decreased renal function in the elderly primarily impacts this pharmacokinetic process, potentially leading to drug accumulation.
What is excretion?
During pregnancy drug clearance can ____ depending on the drug.
What is increase?
The name of the screening tool used to identify potentially inappropriate medications for older adults.
What is the Beer's Criteria?
This term refers to a device commonly used to ensure accurate dosing of liquid medications for children.
What is oral syringe?
This anti-androgen medication is often prescribed to block testosterone effects in transgender women.
What is spironolactone
This medication class should not be taken within 6 months of an MI.
What are PDE-5 Inhibitors?
If a patient is family planning you must ask about ___ before prescribing.
What is last menstrual period?
These types of medications can cause anticholinergic side effects like confusion and dry mouth, posing significant risks to elderly patients.
What are antihistamines?
This organ, responsible for drug metabolism, is immature in neonates, impacting the dosing of medications
What is the liver?
A potential side effect of estrogen therapy in transgender women, especially in smokers or those with other risk factors.
What are blood clots?
Aging-related reductions in plasma albumin levels can lead to increased free drug concentrations for medications that are highly bound to this
What is protein?
When prescribing to a lactating patient an (acidic or basic) drug will have higher concentration in the milk?
What is basic?
Due to decreased lean body mass and increased fat stores, lipophilic drugs leads to ___ half-life in elderly patients.
What is increased half life?
The immaturity of this neonatal barrier increases susceptibility to drug toxicity and infections in the brain.
What is the blood brain barrier?
This hormone is the cornerstone of masculinizing hormone therapy for transgender men.
What is testosterone?
This enzyme system is responsible for metabolizing both estrogens and many other medications, increasing the risk of drug interactions
What is CYP 450?
Medications with ____ half-life should be avoided in lactation.
What is long?
Polypharmacy, defined as the use of multiple medications, is a key risk factor for this preventable phenomenon in older adults.
What are drug to drug interactions?
The gastric pH in neonates is higher (less acidic), affecting the absorption of these types of drugs.
What are weakly acidic drugs?
This hormone should be excluded from birth control for transgender male patients.
What is estrogen?
Too much of this medication can cause liver failure.
What is acetaminophen?