Characteristics/Mechanism of action
Ionization/metabolism
Adverse Reactions
Agents
Miscellaneous
100
aromatic nucleus
What is the lipophilic portion of a local anesthetic?
100
Free base
What is reduced in the presence of infection?
100
Prilocaine and Articaine have the potential to cause what serious adverse reaction?
What is methemoglobinemia?
100
Lidocaine can be used safely for this type of patient?
What is a pregnant woman?
100
5-10%.
What is the amount of articaine metabolized in the liver.
200
Linkage
What is the part of the anesthetic that people can be allergic to if it is an ester?
200
decreased effectiveness of local anesthetic.
What is the effect of a more acidic environment on the effectiveness of local anesthetic?
200
Diphenhydramine (Benadryl).
What is used when a patient reports allergy to all anesthetics?
200
Provides 60-90 minutes duration of pulpal anesthesia?
What is lidocaine?
200
Neither an ester nor an amide.
What is Dyclonine?
300
Potent, reversible, absence of local, systemic, and allergic reactions, sterilizable by autoclave, and rapid onset?
What are some of the properties of an ideal local anesthetic.
300
Cationic portion.
What form of the local anesthetic is necessary to penetrate the nerve membrane.
300
Antioxidant for the vasoconstrictor, which can trigger an acute asthmatic attack?
What is sulfite?
300
The longest duration of action.
What is Bupivacaine
300
Levonordefrin.
What is the vasoconstrictor used with mepivacaine?
400
Axons and Sodium Channels.
What are the sites of the mechanism of action for local anesthetics?
400
Reduce the chance of systemic toxicity.
What is the effect of reducing the rate of systemic absorption of local anesthetic?
400
Beta-adrenergic antagonists and tricyclic antidepressants.
What are the two agents known to cause clinically significant drug interactions when combined with epinephrine?
400
Derived from thiophene?
What is Articaine?
400
Most commonly used topical anesthetic, which can cause systemic toxicity if used on abraded skin.
What is benzocaine?
500
Repolarization
What occurs with the efflux of potassium?
500
The liver.
What is the site of metabolism for amide local anesthetics.
500
2.0 cartridges.
What is the cardiac dose of 1:100,000 epinephrine?
500
Both an ester and an amide.
What is Articaine?
500
Very Much!
How much do you appreciate these Jeopardy Labs?, since they take me forever to make?????????
M
e
n
u