Background
Neurobiology of Loneliness and Reward
Reward System Sensitivity and Loneliness
Loneliness on Social Networks
Future Applications
100

How does the reward network activate?

By Getting a Reward

100

Impaired reward system links loneliness to?

Depression

100

What does BAS mean?

Behavioral Activation Systems

100

How did they do this study?

Through facebook ads? 

100

What can data from social media be used for?

To identify resources which can help alleviate loneliness

200

What does the reward network transport 

Dopamine 

200

What is Oxytocin? 

is a stress regulating hormone that also plays a role in controlling loneliness related neuroinflammation

200

What does a higher reward system lead to? 

more social contact which leads to less loneliness

200

What were smaller involved networks linked to?

Depression

200

What can loneliness-induced depression be identified as? 

Reward” depression for treatment purposes

300

What is the Reward Network also known as?

 Mesolimbic pathway

300

What can low levels of oxytocin lead to? 

Leads to systemic inflammation

300

What were people with higher BAS inclined to? 

those with higher levels of BAS were more inclined toward social engagement due to their heightened reward sensitivity

300

What type of interactions did depressed users get less of?  

Smaller inbound interactions such as receiving likes and comments.

300

What does RST studies suggest? 

Focusing on personality and social factors for treatment

400

Where does the Reward Network transfer dopamine from, and where does it transfer it to?

From the Ventral Tegmental Area (VTA) to the nucleus accumbens, amygdala, hippocampus,

400

How does loneliness contribute to the risk of depression?

Loneliness increases the risk of depression because it impairs the reward system

400

What did the initial studies discover about the Behavioral Inhibition System (BIS), and what did they associate it with?


More sensitive to punishment were less likely to seek out social engagement out of fear of social retribution. They tied it to fear and anxiety. 

400

What does the reward path consist of?

Dorsal anterior cingulate cortex, anterior insula (labeled just insula here), and the amygdala.

400

Define Reward Depression. 

Subtype of depression to focus on treatment options targeting loneliness, more useful than treating depression as an umbrella term

500

What could be the reason for the deactivation of the reward system? What are the effects of its deactivation?


The reward networks stays unactivated in times of loneliness. Less activations of this network and regions cause there to be a lower amount of dopamine in the system which can lead to disorders such as depression and anxiety.

500

How does neuroinflammation affect the reward system and dopamine neurons?

Neuroinflammation affects the reward system by blocking insulin signaling

500

Why didn't high  (BIS) have much relation to loneliness in this study, and what factors were found to increase loneliness instead?


This is because fear and anxiety were two separate indicators in this study. Fear and personal acceptance did lead to heightened loneliness. 

500

How do we reduce inbound interaction? 

Giving outbound support
500

How can social justice groups utilize information about reward systems and loneliness to support marginalized communities?

Directing social programs towards groups like racial minorities and LGBTQ individuals to address their struggles with finding community and targeting reward systems for tangible effects

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