SCLC
NSCLC
Drug Toxicities
Drug Classes
Miscellaneous
100

SCLC is ____ sensitive to chemotherapy and radiation.

What is highly?

100

This type of NSCLC is associated with smoking

What is Squamous Cell Lung Cancer?

100

Gemcitabine is associated with these types of toxicities.

What is hepatotoxicity and pulmonary toxicity?

100

This class includes cisplatin and carboplatin.

What are platinum agents?

100

This type of NSCLC is the most common.

What is adenocarcinoma?

200

This stage of SCLC is not confined to the hemithorax or origin and presents with distant metastasis.

Extensive Stage

200

This form of therapy is the most efficacious modalities for treatment of NSCLC.

What is surgery?
200

This drug is most commonly associated with chemotherapy-induced nausea vomiting as its main toxicity.

What is cisplatin?

200

This class includes paclitaxel and nab-paclitaxel.

What are taxanes?

200

Maintenance therapy is an option for patients that achieve a response or have stable disease in __ cycles.

What is 4 to 6 cycles?

300

SCLC is high sensitive to these forms of therapy.

What is radiation and chemotherapy?

300

This therapy is now considered the standard of care.

What is adjuvant chemotherapy?

300

This drug is associated with neurotoxicity.

What is vinorelbine?

300

This class of medications include neurotoxicity and peripheral neuropathy as toxicities.

What are vinca alkaloids?

300

This medication is dosed with this equation.

What is the Calvert Equation?

400

This medication is most efficacious when given with radiation therapy.

What is Cisplatin?

400

This medication regimen is the preferred regimen for Nonsquamous NSCLC for (neo)adjuvant therapy.

What is cisplatin and pemetrexed?

400

What toxicity is most commonly seen with oxaliplatin?

What is neuropathy?

400

These classes of drugs have toxicities relating to skin, gastrointestinal, endocrine, and liver.

What are PD-1 and PD-L1 Inhibitors?

400

This drug can be used as an alternative when patients have a known hypersensitivity reaction to paclitaxel or docetaxel.

What is nab-paclitaxel?

500

These two forms of therapy do not play a role in therapy of SCLC

What is maintenance chemotherapy and surgery?

500

These are the top three most common mutations or targets seen in clinical practice for NSCLC.

What is EGFR, ALK, and PD-L1?

500
This drug is held until the CrCl is 45ml/min or higher and has toxicities including myelosuppression and interstitial pneumonitis.

What is pemetrexed?

500

This class of medications requires supplementation with folic acid.

What are anti-folates?

500

These medications/supplements are concurrently taken with pemetrexed to avoid toxicities.

What is folic acid, vitamin B12, and dexamethasone?

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