SCLC is ____ sensitive to chemotherapy and radiation.
What is highly?
This type of NSCLC is associated with smoking
What is Squamous Cell Lung Cancer?
Gemcitabine is associated with these types of toxicities.
What is hepatotoxicity and pulmonary toxicity?
This class includes cisplatin and carboplatin.
What are platinum agents?
This type of NSCLC is the most common.
What is adenocarcinoma?
This stage of SCLC is not confined to the hemithorax or origin and presents with distant metastasis.
Extensive Stage
This form of therapy is the most efficacious modalities for treatment of NSCLC.
This drug is most commonly associated with chemotherapy-induced nausea vomiting as its main toxicity.
What is cisplatin?
This class includes paclitaxel and nab-paclitaxel.
What are taxanes?
Maintenance therapy is an option for patients that achieve a response or have stable disease in __ cycles.
What is 4 to 6 cycles?
SCLC is high sensitive to these forms of therapy.
What is radiation and chemotherapy?
This therapy is now considered the standard of care.
What is adjuvant chemotherapy?
This drug is associated with neurotoxicity.
What is vinorelbine?
This class of medications include neurotoxicity and peripheral neuropathy as toxicities.
What are vinca alkaloids?
This medication is dosed with this equation.
What is the Calvert Equation?
This medication is most efficacious when given with radiation therapy.
What is Cisplatin?
This medication regimen is the preferred regimen for Nonsquamous NSCLC for (neo)adjuvant therapy.
What is cisplatin and pemetrexed?
What toxicity is most commonly seen with oxaliplatin?
What is neuropathy?
These classes of drugs have toxicities relating to skin, gastrointestinal, endocrine, and liver.
What are PD-1 and PD-L1 Inhibitors?
This drug can be used as an alternative when patients have a known hypersensitivity reaction to paclitaxel or docetaxel.
What is nab-paclitaxel?
These two forms of therapy do not play a role in therapy of SCLC
What is maintenance chemotherapy and surgery?
These are the top three most common mutations or targets seen in clinical practice for NSCLC.
What is EGFR, ALK, and PD-L1?
What is pemetrexed?
This class of medications requires supplementation with folic acid.
What are anti-folates?
These medications/supplements are concurrently taken with pemetrexed to avoid toxicities.
What is folic acid, vitamin B12, and dexamethasone?