Cells
Macrophages
APCs. Wandering: actively seek pathogens. Fixed: phagocytize pathogens that come to them.
Lymphatic Nodules
Dense groups of lymphocytes and macrophages that come together in response to pathogens. Lymph nodes, tonsils, appendix
Lymph Nodes
Site where B-cells multiply and become plasma cells. Lymph leaves thru hilum
MCH I and MCH II
MCH I presents a self-antigen to T-Cell; MCH II presents a foreign antigen
Collecting Ducts
The final, largest vessels that transport lymph from smaller vessels back into the blood stream via. the internal jugular, or subclavian
NK Cells
Constantly patrol the body, look for pathogens/infected host cells. Release perforins and create a hole in the enemy and secrete granzymes that apoptize the pathogen.
Peyer Patches
Dense clusters of lymphatic nodules in the ileum
Red Marrow
Primary organ;Where lymphocytes are born and mature. Hemopoiesis and immunity
Lymphadentitis
Swollen, painful node responding to foreign antigen
Thoracic Ducts
Largest lymphatic vessel, transports lymph (fat, immune cells, fluid) from lower body/abdomen, back to the veins
Dendritic Cells
Branched, mobile APCs found in the epidermis, mucous membranes, and lymphatic organs. Alert the immune sys.
Diffuse Lymphatic Tissue
Lymphocytes aren't in clusters, MALT (mucosa associated tissue), prevalent in open body passages.
Thymus
Primary organ; where T-cells become immunocompetent. Produce interferons and interleukins
Lymphodenopathy
Collective term for lymph node diseases
Order of Lymphatic Drainage
Lymphatic capillary, vessel, duct, collecting duct, subclavian vein
Reticular Cells
Branched stationary cells that contribute to the stroma of a lymphatic organ
SALT BALT GALT, MALT
Lymphoid tissue for immune function in skin; respiratory tract, intestines (peyer's patches); and mucosa (umbrella term)
Spleen
Parenchyma: 2 types of tissue. Red pulp: filled w/ RBCs. White pulp: lymphocytes + macrophages.
Metastasis
When cancerous cells break free from a tumor and go into the pores of lymph vessels, then attack lymph nodes
6 Lymphatic Trunks
Jugular, subclavian, bronchomediastinal, intercostal, intestinal, lumbar
T Lymphocytes
Adaptive immune cells that identify specific antigens presented on APC surfaces. Activate clonal expansion. CD4+ start the response, CD8+ kill the infected cell.
Lactiles
Absorb dietary fats, metabolize lipids, located in the small intestine.
Tonsils
Guard against pathogens, have deep pits. Palantine, lingual, and pharyngeal (adenoid) tonsils
Cisterna Chyli
Sac-like lymphatic vessel in upper lumbar region, collects lymph from lower body and intestinal tracts.