PHARMACOLOGY
WHAT IS THE DRUG TO TREAT MALIGNANT HYPERTHERMIA CALLED AND HOW MANY MG ARE IN EACH VIAL?
RYANODEX IN 250MG VIALS
WHAT OTHER DISORDER HAS MALIGNANT HYPERTHERMIA BEEN LINKED TO?
MUSCULAR DYSTROPHY
WILL THE PATIENT IN MALIGNANT HYPERTHERMIA PRESENT WITH MUSCLE WEAKNESS OR MUSCLE RIGIDITY?
MUSCLE RIGIDITY
WHAT IS THE FIRST THING YOU SHOULD DO WHEN MALIGNANT HYPERTHERMIA IS SUSPECTED?
STOP THE PROCEDURE/TRIGGERING AGENT
MALIGNANT HYPERTHERMIA IS ALSO FOUND IN WHAT TWO ANIMALS?
PIGS AND HORSES
WHAT DO YOU DILUTE A VIAL OF RYANODEX WITH AND WITH HOW MANY ML'S?
5ML OF STERILE WATER (without a bacteriostatic agent)
WHAT TRIGGERS MALIGNANT HYPERTHERMIA IN PATIENTS? WHICH DRUG SPECIFICALLY?
GENERAL ANESTHESIA /SUCCINYLCHOLINE
THE PATIENT IN MALIGNANT HYPERTHERMIA STARTS TO SHOW VERY DARK URINE. WHAT IS THIS CALLED?
RHABDOMYOLYSIS
WHAT SHOULD YOU DO WITH THE PATIENT'S OXYGEN WHEN MALIGNANT HYPERTHERMIA IS SUSPECTED?
HYPERVENTILATE WITH 100% O2
HOW HIGH HAS THE TEMPERATURE BEEN SEEN TO GET IN MALIGNANT HYPERTHERMIA?
UP TO 110 DEGREES
WHAT IS THE CORRECT WEIGHT BASED STARTING DOSE FOR DANTROLENE?
2.5 MG PER KG
HOW MANY DIFFERENT GENETIC DEFECTS ARE ASSOCIATED WITH MALIGNANT HYPERTHERMIA?
80
WHAT IS THE FIRST SIGN OFTEN SEEN IN MALIGNANT HYPERTHERMIA?
RISING END TIDAL CO2
HOW MANY TOTAL VIALS OF RYANODEX SHOULD ALWAYS BE IN THE M.H. CART?
3 VIALS
ONE IN HOW MANY PATIENTS HARBOR THE GENETIC CHANGE THAT MAKES THEM SUSCEPTIBLE TO MALIGNANT HYPERTHERMIA?
1 IN 2,000 PEOPLE
YOUR PATIENT WEIGHS 60KG. WHAT IS THEIR STARTING DOSE OF RYANODEX?
2.5MG X 70KG= 150MG
THE BUILDUP OF WHAT MINERAL CAUSES MUSCULAR RIGIDITY IN MALIGNANT HYPERTHERMIA?
CALCIUM
WHAT IS OFTEN THE CAUSE OF ARRYTHMIAS IN A PATIENT WITH MALIGNANT HYPERTHERMIA?
A MASSIVE CATECHOLAMINE SURGE
YOU STABILIZE YOUR PATIENT IN MALIGNANT HYPERTHERMIA, WHAT IS THE NEXT STEP?
A. SEND THEM TO PACU TO RECOVER
B. ADMIT THEM TO MED-SURG
C. RECOVER THEM FROM THE PROCEDURE AND SEND PATIENT HOME AS LONG AS THEY'RE STABLE
D. ADMIT THEM TO ICU
D. ICU. THEY WILL NEED THE HIGHEST LEVEL OF CARE.
WHAT IS THE NORMAL RANGE OF ETCO2?
35-45 mmHG
YOUR PATIENT WEIGHS 50KG. HOW MANY VIALS OF RYANODEX WOULD YOU NEED FOR THIS PATIENT?
(THIS IS A MULTI-STEP MATH PROBLEM)
50 KG X 2.5MG = 125 MG DOSE
250MG PER VIAL
ANSWER= 1 VIAL
WHAT CLOTTING DISORDER CAN PATIENTS GO INTO AS A RESULT OF MALIGNANT HYPERTHERMIA?
DISSEMINATED INTRAVASCULAR COAGULATION (DIC)
YOUR PATIENTS JAW APPEARS TO GET TIGHT AND RIGID DUE TO MALIGNANT HYPERTHERMIA. WHAT IS THE NAME OF THIS CONDITION?
MASSETER MUSCLE TENSION
WHERE SHOULD YOU REFER THE PATIENT AND THEIR FAMILY AFTER A MALIGNANT HYPERTHERMIA EVENT?
MHAUS/ MALIGNANT HYPERTHERMIA ASSOCIATION OF THE UNITED STATES
WHAT RESPIRATORY AND METABOLIC CHANGES HAPPEN IN MALIGNANT HYPERTHERMIA?
A. RESP ACIDOSIS AND METABOLIC ALKALOSIS
B. RESP ALKALOSIS AND METABOLIC ACIDOSIS
C. RESP ACIDOSIS AND METABOLIC ACIDOSIS
D. RESP ALKALOSIS AND METABOLIC ALKALOSIS
C. RESP ACIDOSIS/ METABOLIC ACIDOSIS