Intro to MH
Patient's most susceptible to MH crisis may have this autosomal disorder because?
What is: Its inherited
Name 2 early clinical signs of MH crisis, not including increased ETCO2.
What is: tachycardia, muscle rigidity
Medication for Malignant hyperthermia
What is: Dantrolene, Ryanodex (250mg per vial)
The MH cart contains how many vials of Dantrolene?
What is: 1
The MH cart for the OR is shared with what other departments?
What is: Endo, cath lab/IR
Name a very early, measurable clinical sign of an impending MH crisis, mainly noted first by an Anesthesiologist.
What is: increase CO2 level
When a MH crisis is suspected the anesthesiologist must do this ________, as soon as possible.
What is: stop the triggering agent, hyperventilate with 100% oxygen at a high rate.
Dantrolene can only be mixed with this.
What is: Non bacteriostatic water (5ml)
These are 2 non triggering agents
What is: Propofol, ketamine
Name two other medications needed during an MH crisis
What is: Calcium chloride (1Gm) for arrhythmias, Sodium Bicarb (1-2 mg/kg) for metabolic acidosis, Insulin, Dextrose
In MH, what 2 substances are released into the body at an increased and rapid rate.
What are: Calcium and Potassium
one of the first things the circulator needs to get for the treatment of MH?
What is: The Malignant hyperthermia cart/Crash cart
This should be orange
What is: The color of Dantrolene after being shaken for 20-30 seconds.
1 in 3000
What is: The number of people predisposed to MH
Less than 5%
What is: The mortality rate if found early
Known triggers of a MH crisis.
What is: Sevoflurane and Desflurane, and Succinylcholine
If a patient has a high fever, you need to perform this type of measure to decrease temperature.
What is: Apply ice packs
The initial starting dose of dantrolene
What is: Dantrolene
2.5 mg/kg IV bolus ASAP
Around 700
What is: The number of MH cases per year.
1-800-MH-HYPER
What is: The MH hotline is open 24/7 365 and may be called during a MH crisis.
The cause of muscle rigidity
What is: The release of calcium from the muscles
Name 3 areas to apply ice to patient for cooling.
What is: Axillary, groin, side of neck
The repeat dose of Dantrolene
What is: 2.5mg/kg bolus every 2-3 minutes until symptoms subside or 10mg/kg is reached.
A patient from Wisconsin is at a higher or lower risk for MH.
What is: higher (Wisconsin, Michigan, and West Virginia)
The amount of Dantrolene to continue after a crisis.
What is: 1mk/kg IV q4-6 hours for 24 hours