Nailed it
Potpourri
Warts and Crafts
Think Positive
Welcome to Moh's
100
Brachynychia (Racquet Nails); Shortening of the distal phalanx. Where length of nail < width of nail. Seen in patients with Rubinstein-Tabi syndrome.
100
#1 tumor of oral cavity
Oral Fibromas - pink papule along bite line in buccal mucosa.
100
These strains are included in the HPV vaccine (specify which vaccine). bonus- how does vaccine work?
Gardasil: HPV 6,11,16,18
Bivalent: Cervarix HPV 16, 18
9 valent: 6,11,16,18,31,33,45,52,58
Works by L1 capsid protein causing immune response (no HPV DNA)
100
Don't Sweat this stain, positive in sweat gland neoplasms and Paget's.
CEA
100
You may feel depressed if you lose the function of this muscle to depress your jaw and express melancholy.
Platysma!
200
Patient comes to see you with these nail findings, also has renal dysfunction and arthritis.
Mutation in LMX1B (autosomal dominant)
Nail-Patella Syndrome
Associated with arthritis, renal dysfunction, lester iris (pigment at pupillary margin of iris).
200
Most common mutation in superficial spreading melanoma
BRAF (600VE)
Other mutations to know:
200
Your local butcher wants to know what kind of HPV is responsible for his warts - you reply:
HPV 7 and HPV2
200
Where'd you go? This marker is lost in Scleroderma and Morphea.
CD34 - lost in scleroderma/morphea, gained in NSF and scleromyxedema
200
If you're looking for high tensile strength - opt for this non-absorbable suture.
How about absorbable suture:
Polyester (Ethibond)
Polyglecaprone-25 (Monocryl)
300
Nail pterygium unguis - scarring beween eponychium and matrix (LP)
Pterygium inversum unguis - attachment of distal nailed to ventral nail plate (scleroderma)
300
#1 Shoe dermatitis
Mercaptobenzothiazole (MBT)
300
Oh, Heck - more oral warts. What strain of HPV is to blame?
HPV 13 and HPV 32 (Heck's disease)
Oral warts HPV 6,11
300
Donate your answers for plasma cell markers.
CD138, CD79a. CD45
300
Not to undermine this topic- but how far should you undermine on a closure on the face.
Superficial subcutaneous plane superficial to SMAS (superficial musculoaponeurotic system)
400
A glassworker develops torsades. After stabilizing him, you notice the following nail findings. What is your suspicion.
Arsenic Poisoning - 2-3 weeks after acute exposure (Mee's lines)
400
Imiquimod activates TLR __& _____ in order to increase cytokines such as _______
TLR 7 & 8 , increase TNF alpha and IFN gamma.
400
________ proteins are responsible for for DNA replication and keratinocyte immortalization.
E1-E7.
400
Spencer would use these stains naturally to find NK cells on biopsy:
CD56, CD57
granzyme (A/B) TIA-1 (also CD8+ cells)
400
This anethestic has the longest duration of action..careful with dosing it also has the highest risk of cardiac toxicity.
Bupivicaine - up to 8 hrs with epi.
500
Subungal Exoctosis - XRAY for diagnosis.
500
You are called to investigate an outbreak of systemic sclerosis, raynauds and pulmonary fibrosis at a local factory. You suspect they manufacture this chemical
Polyvinyl Chloride
500
Name the style of Japanese pottery featured below:
Raku Ceramics.
500
Biopsy Stain of choice for degranulated mast cells
Leder (chloracetate esterase) or CD117 (c-kit)
500
It's going to be a while...this anesthetic has the slowest onset of action.
Mepivacaine (3-20 minutes)