OBGYN
Pregnant patient that is past 20 weeks gestation presents with HTN. Define 2 features that characterizes pre-eclampsia without severe features
Sustained hypertension >140/90
Kidney injury/proteinuria (>300mg/dL)
This lab abnormality—elevated carboxyhemoglobin—is seen in this type of poisoning from enclosed-space fires
What is carbon monoxide poisoning?
This postpartum pituitary infarction presents with failure to lactate after severe hemorrhage
What is Sheehan syndrome?
This mitochondrial toxin exposure, commonly found in anti-freeze, causes severe lactic acidosis and optic neuropathy in chronic alcohol users
What is methanol toxicity?
This postpartum headache with seizures is diagnosed with MR venography
What is cerebral venous sinus thrombosis?
This antidote is used for acetaminophen overdose and works by replenishing glutathione
What is N-acetylcysteine (NAC)?
This autoimmune encephalitis presents with psychosis, seizures, and ovarian teratoma in young women
What is anti-NMDA receptor encephalitis?
Elderly patients that are taking amitriptyline are at risk for TCA toxicity, which presents with anticholinergic effects (dry skin, dilated pupils, fever), hypotension, cardiac toxicity (prolonged QTc or arrhythmias), and AMS. Name an important diagnostic test that should be ordered.
What is an EKG, CMP, tests to rule out other co-intoxications (RUDS, tylenol levels, salicylate levels), +/- head CT non-con
Name ONE teratogenic medication that should be avoided during pregnancy for each of the following medical conditions:
1. Hypertension
2. Seizures
3. Antibiotics
4. Lupus
1. ACE/ARBs
2. Valproate sodium, phenytoin, phenobarbital, carbamazapine, topiramate
3. Bactrim, aminoglycosides (streptomycin, gentamicin), tetramycin
4. Methotrexate
This rare cause of chronic acetaminophen use leads to elevated 5-oxoproline and normal anion gap metabolic acidosis
What is pyroglutamic acidosis?