Terminology
Cells that accumulate aberrantly and invade local or distant tissues (metastasize)
What are cancers?
A pipette is used to transfer a substance of interest from one container to another, with the solution becoming more diluted with each transfer.
What are serial dilutions?
Differences in the incidence, prevalence, mortality, and burden of disease and other adverse health conditions that exist among specific population groups.
What is Health Disparity?
Name the 3 most common types of cancer worldwide.
What are breast, prostate, and lung cancer?
Tiny single-celled living organisms — so small you can't see them without a microscope
What are bacteria?
The term for a cancerous tumor.
What is malignant?
List everything you must write on a bacterial culture plate with before plating.
What are your first and last name, the date, the bacteria type(s), and the media type?
A partnership approach to research that equitably involves all participants in all aspects of the research process where each person shares his/her expertise in order to enhance knowledge and develop interventions that will benefit the whole community.
Community Based Participatory Research
Name the 3 main causes of cancer.
What are Age, Lifestyle, and Bad Luck?
The total number of chromosomes in one somatic cell of the human body
What is 46- or 23 pairs?
A state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity.
What is health?
At least the 1947 definition published by the WHO
This portion of PCR seperates the strands of DNA.
What is denaturation?
The conditions in which people are born, grow, work, live, and age, and the wider set of forces and systems shaping the conditions of daily life.
What are the social determinants of health?
The percentage of solid tumors
What is 85%?
List the 4 nucleotides present in DNA.
What are adenine, thymine, cytosine, and guanine?
The suffix for a solid tumor
What is 'oma'
The sets of chromosomes in a strawberry.
What is 8- aka octoploid-?
The Race/ Ethnicity with the highest cancer mortality rate in MN for both males and females.
What is AIAN? (American Indian and Alaskan Native)
What is the TP53 gene?
The two processes that are often called the central dogma of biology
What are transcription and translation?
Change of a single DNA base pair that results in a change in the amino acid sequence.
What is a missense mutation?
Name 4 of the 6 Lab Safety Guidelines covered in lab day 2.
(Hint: These are also just general guidelines you should follow in any lab)
1) Always wear closed-toed shoes and long pants
2) No food or drink in the lab
3) Label everything
4) Tell an instructor/ PI/ mentor/ supervisor if you spill or break anything
5) Tie back hair and avoid or tie back loose clothing
6) Where gloves whenever touching lab materials or working with chemicals
Name the six steps of the Cancer Continuum, as described by Dr. Michele Allen.
What are: Etiology, Prevention, Screening, Therapy, Survivorship, and Palliative care?
Name 5 of the 10 hallmarks of cancer.
What are:
1. Invasion and metasis
2. Inflammation
3. Enabling replicative immortality
4. Angiogenesis induction
5. Sustaining proliferative signaling
6. Evading Immune Destruction
7. Metabolism reprogramming
8. Cell death resistance
9. Evading growth suppressors
10. Genome instability
The length of the human genome, in base pairs.
What is ~3.2 Billion BP?