Methadone
Suboxone
Naltrexone
Other Meds
General
100
Methadone is used for the treatment of which substance use disorder?
Opiate Use Disorder (OUD)
100
Suboxone is used for the treatment of which substance use disorder?
Opiate Use Disorder (OUD)
100
Naltrexone is used for the treatment of which substance use disorder?
Alcohol use disorder (AUD) and Opiate use disorder (OUD)
100
This medication is the recommended choice for stimulant cravings
Topamax (topiramate)
100
True or False: MAT is just replacing one drug with another
FALSE
MAT medications are evidence based and FDA approved
200
True or false: Methadone has a longer half life than most other opioids
TRUE
200
This is the long-acting injectable form of suboxone
Sublocade and Brixadi
200
This is the long acting injectable form of Naltrexone
Vivitrol
200
This medication is similar to suboxone, but “without the blocker”
Subutex
200
True or False: MAT medications are effective on their own, there is no need for AA/NA, therapy, etc
FALSE
All MAT works best in conjunction with other treatment
300
At High Point, what do you need to have established before starting methadone maintenance?
A home clinic
300
What are the two medications that make up suboxone?
Buprenorphine and Naloxone
300
This is the recommended dose for Naltrexone pills
50mg once a day
300
This medication blocks the enzyme that breaks down alcohol, causing severe illness if a person drinks while taking it
Antabuse
300
MAT has been shown to reduce risks of certain infectious diseases - name one of these
HIV
Hep C
Hep B
400
This is the length of time it takes to feel the full effect of a dose increase
Approximately 7 days
400
How long should you abstain from opioids before starting suboxone?
Minimum of 12 hours, ideally 24-48 hours
400
Name one of two blood tests required before starting naltrexone
LFTs (Liver function test)
CBC (complete blood count)
400
Campral is a pill used to reduce alcohol cravings. How many times a day is it taken?
Three
400
True or False: Over 2 million Americans were prescribed MAT in 2023
True - Approx. 2.3 million people in the US were prescribed MAT in 2023
500
An EKG might be required before a dose increase to assess for which potential side effect?
QT Prolongation
500
True or False: It is only the naloxone in suboxone that can cause precipitated withdrawal
FALSE
Buprenorphine is a partial opioid agonist - it has a higher affinity for opioid receptors and will knock other opioids off
500
Vivitrol carries a high risk warning for overdose - what is the reason?
It blocks opioids from binding to the receptors - repeated use to “break through” causes opioids to build up. Once they “break through”, this higher volume all binds at once, causing an overdose
500
This is another long acting form of buprenorphine that can be taken in weekly, biweekly, or monthly dosing
Brixadi
500
This is the name of the receptors that MOUD such as methadone or suboxone bind to in the brain
Mu - opioid receptors