Matcha carbonyls
Reaction occurs when a nucleophile attacks the carbonyl carbon of an aldehyde
What is nucleophilic addition?
This type of reaction replaces a hydrogen on benzene with another substituent.
What is electrophilic aromatic substitution?
The many -OH groups attached to aromatic rings in catechins belong to this functional group.
What is a phenol?
This reagent oxidizes a primary alcohol to a carboxylic acid.
What is KMnO4 or Jones reagent?
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Reducing an aldehyde with NaBH4 produces this type of compound.
What is a primary alcohol?
The reagent Br2/FeBr3 performs this reaction on benzene.
What is bromination?
The bond connecting the gallete portion to the catechin in EGCG is this functional group.
What is an ester?
This reagent reduces carboxylic acids and esters to primary alcohols.
What is LiAlH4?
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This reaction forms a B-hydroxy carbonyl by combining two aldehydes or ketones.
What is an aldol reaction?
Groups like -OH and -NH2 direct substitution to these positions.
What are ortho/para positions?
L-tehaenine contains this nitrogen-containing functional group common in amino acids.
What is an amine?
What is Fischer Esterification?
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Heating an aldol product often causes this reaction to form an a,B-unsaturated carbonyl.
What is aldol condensation (dehydration)?
The NO2 group directs substitution to this position?
What is the meta position?
What is an amide?
If a chemist wanted to convert the carboxylic acid portion of a tea polyphenol into a more reactive carbonyl derivative for further synthesis, they might convert it into this compound using SOCl2.
What is an acid chloride?
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When the ester carbonyl in EGCG reacts with a strong nucleophile like hydroxide, the reaction forms a carboxylate and an alcohol through this type of carbonyl reaction.
What is nucleophilic acyl substitution?
To add a carbonyl-containing substituent onto an aromatic ring like the phenol rings found in catechins, chemists can react benzene with an acyl chloride and AlCl3 in this electrophilic aromatic substitution reaction.
What is Friedel-Crafts acylation?
Caffeine contains several nitrogen atoms in rings, making it part of this class of nitrogen-containing natural compounds.
What are alkaloids?
To synthesize a more complex catechin derivative in the lab, a chemist performs a crossed aldol reaction between an aldehyde from one tea molecule and a ketone from another, forming a new a,B-unsaturated carbonyl after dehydration. This reaction is...
What is a mixed (crossed) aldol condensation?
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