Bio for Beginners
Useful Germs
Famous Microbiologists
Tools, Devices, and Dyes
Disease
100

This is where the smallest bones in the body are located.

The ears

100

This useful rod bacteria is the most widely studied prokaryotic model organism and is found in many biotechnology and microbiology labs.

E. Coli

100

This man was the first to look at cells under a microscope.

Antonie van Leeuwenhoek

100

This tool, found in practically every biology and chemistry lab, is used to measure and move small amounts of liquid from one place or reaction to another.

Pipette

100

This virus type is the most frequent cause of the common cold.

Rhinovirus
200

This cell type is the longest in the body.

Neuron

200

Commonly called "baker's (or brewer's) yeast", this fungus has wide applications in the food industry.

Saccharomyces cerevisiae

200

This man is credited as the "father of germ theory", and disproved spontaneous generation.

Louis Pasteur

200

This long, thin tool is used to streak bacteria on a plate.

Inoculation loop

200
This is the formal name for pinkeye.

Conjunctivitis

300

This is the name of any substance (usually produced by bacteria) that causes fever.

Pyrogen

300

Some species of this lactic acid producing genus are used to produce cheese, kefir, and other fermented products.

Lactobacillus

300

This woman discovered X inactivation and developed the theory behind female carriers of X linked diseases.

Despite her doing the same amount of work as her male counterparts, she was not allowed to earn a full degree at Cambridge, and transferred to study elsewhere.

Mary Lyon

300

This dye is retained in the walls of gram positive bacteria during Gram staining.

Crystal violet

300

This disease results in the accumulation of uric acid crystals in the joints

Gout

400

This hollow, woody tissue carries water and minerals from the ground to the rest of the plant.

Xylem

400

This gene delivery system is made from the HIV-1 virus.

Lentiviral vector system
400

This man discovered phagocytes (specifically the macrophage) and is known as the "father of innate immunity".

Élie Metchnikoff

400

This machine is necessary to amplify DNA fragments via PCR.

Thermocycler

400

This bacteria causes Lyme disease. (+100 points if you can guess the bacterial shape)

Borrelia burgdorferi (it's a spirochete!)

500

A common misconception about butterflies is that they pupate in cocoons. Butterflies actually pupate in this structure. (+200 points if you can guess which critter pupates in a cocoon!)

Chrysalis (and moths pupate in cocoons!)

500

This immortalized cell line is often used in gene transfection due to its quick growth and consistent reliability.

HEK 293

500

This woman discovered the lambda phage, a bacteriophage that infects E. coli, and the F plasmid, used in bacterial conjugation.

Her results are often misattributed to her husband, and she was never offered tenure.

Esther Lederberg

500

This machine reorients atomic nuclei with non-zero spin using a magnetic field to provide information about functional groups within a protein.

NMR spectrometer

500

Mycobacterium leprae is the bacteria that causes leprosy. The difference between tuberculoid leprosy (less severe) and lepromatous leprosy (more severe) is due to a differentiation failure of this immune cell.

T helper (TH) cells

TH1 cells dominate the tuberculoid leprosy response, and TH2 cells dominate the lepromatous leprosy response. When TH cells differentiate into TH1 cells, they are more suited to deal with the infection (these cells specialize in intracellular pathogens). When they differentiate into TH2 cells, they are less suited to deal with the infection (these cells specialize in multicellular parasites) and the infection becomes more severe.

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