Mitosis and Meiosis
Crossing over occurs in this phase of cell division.
What is Prophase I of Meiosis?
This step in cell signaling can activate an enzyme or turn on transcription of a gene.
What is response?
This enzyme helps to unzip the 2 strand of DNA.
What is helicase?
This type of protein fiber is composed of a double- helix of actin monomers.
What are microfilaments?
A cancer causing gene.
What is an oncogene?
The type of cells that undergo Mitosis.
What are Somatic cells?
This type of molecule will find its receptor in the cytoplasm.
What is a Non-polar molecule?
DNA synthesis occurs in the _____ direction for the leading strand and the _____direction for the lagging strand.
5’ → 3’; 5’ → 3’
This motor protein is associated with microtubules and moves cargo towards the plus end.
What is kinesin?
This type of junction creates a water tight seal between two adjacent cells.
Pairs of chromes that have the same genes, in the same order, although the version of the genes may differ.
What are Homologous Chromosomes?
This type of junction is an example of contact dependent signaling.
What is a gap junction?
DNA synthesis for the leading strand is _________ and for the lagging strand is _________.
continuous; discontinuous
The cell will not divide if it lacks this type of protein fiber.
what are microfilaments (actin)?
This checkpoint ensures chromosomes are lined up at the metaphase plate and the spindles have attached correctly.
What is the M Phase Checkpoint?
Once neurons mature, they will not undergo mitosis, in which phase of the cell cycle will mature neurons be found?
G0 phase
this type of signal receptor often transmits signals by modifying levels of cyclic-AMP, a secondary messenger.
What is a G-protein coupled receptor?
This enzyme completes the covalent bond connecting the sugar phosphate backbone of adjacent Okazaki fragments together during replication.
What is DNA Ligase?
The most diverse component of the cytoskeleton
What are Intermediate Filaments?
What is a Cyclin-Dependent Kinase (CDK)
A drug blocks the assembly of microtubules leading to the arrest of mitosis. At what stage of mitosis would you predict the arrest would occur?
Prophase
Phosphatase is an enzyme that removes a phosphate from a protein. Triuvec is a drug that inhibits phosphatase. What effect would Triuvec Have on the Response of cells to signals received by GCPRS?
The response of the cell would last longer than it normally would.
Given the following DNA strand, what will be the sequence synthesized by DNA polymerase?
5’ - AAGTCCCATGGATCA - 3’
5’ - TGATCCATGGGACTT - 3’
Lengthening and shortening of microtubules can be affected by anti-cancer drugs. These drugs block cell division and the cell cycle stalls. What is happening to dividing cells treated with anti-cancer drugs?
The cells cannot proceed through the spindle assembly checkpoint and stop dividing.
The amount of _______ is fairly constant throughout the cell cycle, but the amount of ______ varies.
Cyclin-dependent Kinase; Cyclins