Hemoglobin level in which ESAs are indicated in CKD-related anemia and goal hemoglobin to target?
Hb < 10; Goal to target Hb 10-11;
* Targeting Hb > 11 has been associated with increased CV risk
The probability of a diagnostic test to correctly say a patient does not have a disease in comparison to all patients without said disease
Specificity
* Sp = (TN/TN+FP)
Equation for MAP

18th century English physician who created the smallpox vaccine and considered the father of immunology
Edward Jenner
Standardized metric to quantify total daily opioid usage and can be used to convert as an intermediary between opioids
MME (Morphine Milligrams Equivalent)
Mentzer Index

The inverse of absolute risk reduction
NNT (Number needed to treat)
* NNT = 1/ARR
2014 landmark trial that showed sacubitril-valsartan decreased CV death and HF hospitalization compared to enalapril in patients with LVEF < 40%
PARADIGM-HF
Passed in 1986, this federal law mandates all Medicare accepting hospitals to see, stablize, and appropriately dispo patients, regardless of insurance status or ability to pay
EMTALA (Emergency Medical Treatment and Labor Act)
Scoring system to help determine severity of opioid withdrawal
COWS (Clinical Opiate Withdrawal Scale)
* Analgous to CIWA for EtOH withdrawal
Eponym given to the criteria used to define Tumor Lysis Syndrome
Cairo-Bishop Criteria
Diagnostic test performance indicators that are NOT affected by prevalence of disease
Sensitivity and Specificity![]()
Thiazide-like diuretic that can be used to augment diuresis in patients developing resistance to loop-diuretics
Metolazone
*Strategy is known as "Sequential Nephron Blockade"
First state in the US to pass "Death with Dignity" laws
Oregon
* Watch "How to Die in Oregon"!
Analgesic agent classically associated with hypoglycemia and increased risk of serotonin syndrome
Tramadol
Genetic syndrome suggested by inability to obtain therapeutic aPTTs while on a heparin drip, defined as >35,000 units over 24 hours
Anti-thrombin III Deficiency
Graph that plots sensitivity vs. 1-specificity where the area under the curve (AUC) calculated can determine test discrimination
Receiver Operating Characteristic (ROC) Curve

Valvulopathy that is a contraindication to IABP
Severe Aortic Regurgitation
* The balloon in an IABP inflates during diastole to help increase coronary perfusion pressure and normally aortic valve is closed, but with an incompetent valve will primarily back flow into the left ventricle
Insulin
Ethical principle that justifies an action with both a beneficial effect and a harmful effect when the beneficial effect cannot be achieved without the harmful effect
Doctrine of Double Effect
* e.g., opioids decrease pain and air hunger but might hasten death
Recently discovered adult-onset auto-inflammatory disorder caused by somatic mutations in UBA1 gene, presenting with systemic inflammation, cytopenia, and is similar to MDS, typically presenting in older men
VEXAS Syndrome
* (Vacuoles, E1 enzyme, X-linked, Auto-inflammatory, Somatic)
Name of this graph that uses LR and a pre-test probability to give a post-test probability
Fagan Nomogram
40-year-old patient presenting with syncope, this is his EKG, diagnosis?

Arrythmogenic Right Ventricular Cardiomyopathy (ARVC)
Four humors previously thought to be the make-up of human bodies
Blood, Phlegm, Yellow-Bile, Black-Bile
* Extrapolation by Hippocrates that just as there were four elements that govern the world as proposed by Pythagoras (air, water, fire, earth), there are four humors that govern the human body
Contraindication for the use of methylnaltrexone or naloxegol
Mechanical bowel obstruction, or those at increased risk of having one
* Increases risk of perforation