Mary Jane Laws
Congress passes Marijuana Tax Act
1937
Number of Americans are regular consumers of Cannabis
48 million
Ischemic and hemorrhagic stroke have been described in association with cannabis use, particularly in
young individuals
Potential Increase THC concentration with __________
CYP3A4 and CYP2C9 inhibitors
They’re considered the “heart and soul of cannabis retail” and “the face of a cannabis dispensary.”
Budtenders
Congress passes Control Substance Act
1970
Number of more daily chronic users
18 million
Cannabis arteritis presenting with Raynaud's and digital ulcerations may indicate induced_________.
thromboangiitis obliterans-like condition.
CYP2C9 Inducers (e.g. rifamycins, barbiturates, carbamazepine) effect THC levels
May Decrease THC levels, attenuating psychoactive effects
Minors, Pregnant Patients, and Seniors are considered
At risk populations
California becomes first state to legalize medical marijuana
1996
Number of Americans suffer from Cannabinoid Hyperemesis Syndrome
1.6 million
The use of cannabis is not without its risks of occasional serious medical emergencies and
sudden death
CYP2C9 Substrates (e.g. warfarin, rosuvastatin, phenytoin)
THC may increase levels; monitor for adverse reactions; dose reduction may be required.
This applies to Retail Cannabis Industry for Medical Use
HIPPA
Cole memo publishes Hands Off Rule
2013
Cannabis flowers sold in retail establishments have a potency between
10-30%
In addition, many cases of stroke and vascular arteritis have also been reported with the latter often involving .
a limb amputation
CYP2B6 substrates (e.g. ,methadone, selegiline, meperidine) may
THC may increase levels; monitor for adverse reactions; dose reduction may be required.
Medical cannabis physicians must provide
Contact information for their medical practice
State that is the 6th largest economy in the world from legalized recreational marijuana
California
How many states, as well the District of Columbia and Puerto Rico, have medical marijuana programs
41
Doctors also noticed that individuals with CHS would take ________hot showers and baths.
6-8
CYP1A2 substrates e.g. (clozapine, theophylline, olanzapine)
Smoked marijuana may increase clearance of these drugs.
Medical associations or a state health department often oversees____________.
medical marijuana training