contrasting prefixes
Disease Conditions
plural v singular
100

ab v ad

ab = abnormal

ad = addiction

100

sign  

symptom  

syndrome

sign—objective evidence, such as a fever

Symptom—subjective evidence of disease (pain, headache), and can ONLY be evaluated by the patient. 

 syndrome—a set of signs and symptoms that occur together as part of a specific disease process

100

If the singular term ends in the suffix "a," then the plural is usually formed by changing the ending to___.

ae as in bursa (fluidlike sac or saclike cavity) versus bursae

e.g. bursitis—inflammation of a bursa, typically ib the knee, elbow, or shoulder  

200

dys v. eu

dys = bad, difficult, or painful

e.g. dysfunctional

eu =good, normal well, or easy

e.g. Eupenea means easy or normal breathing

200

diagnosis

differential diagnosis

prognosis

diagnosis—identification of a disease

differential diagnosis—(D/DX) also known as a rule out (R/O); is an attempt to determine which one of several possible diseases is causing the signs and symptoms that are present

prognosis—the prediction and probable course and outcome of a disease 

200

If the singular term ending in the suffix "ex" or "ix," the plural is usually formed by changing these endings to _______? 

ices

e.g. appendix becomes appendices

index becomes indices

300

hyper v. hypo

hyper = excessive or increased

hypo = deficient or decreased

e.g hypertension = high blood pressure

hypotension = low blood pressure

300

acute

chronic

remission

acute—a condition that has a rapid onset, a svere course, and a relatively short duration

chronic—a condition of long duration. Controlled but rarely cured.

remission—the temporary, partial, or complete disappearance of the symptoms of a disease without having achieved a cure

300

If the singular term ends in "is," the plural is usually formed by changing these endings to _______. 

es

e.g. diagnosis to diagnoses

metastasis to metastases

400

inter v. intra

inter = between or among 

e.g. interstitial—between but not within the parts of a tissue

intra = within or inside

e.g. Supracoststal—above the ribs

400

disease

eponym

acronym

disease—disease in which one or more body parts are not functioning normally. somediseases are named for their signs and symptoms sucha as chronic fatigue syndrome

eponym—a disease, structure, or operation named for the person who described it first like Alzeheimer's

acronym—a word formed from the initial letters such as LASER—Light Amplification by Stimulated Emission of Radiation

400

If the singular term ends in the suffix "itis," the plural is usually formed by changing the "is" to ________

ides

e.g arthritis to arthrides

meningitis to meninggitides

500

dextro v. sinistro

dextro—right side

sinistro—left side

dextroscoliosis—spinal curve bending to the right

sinistropedal—preferential use of the left foot

500

fissure 

fistula

fissure— (1) a groove or crack-like sore of the skin

              (2) normal folds in the contours of the                            brain

fistula—an abnormal passage between two internal organs or leading from an organ to the surgace of the body. May be due to surgery, injury, or draining an abscess 

500

If the singular term ends in the suffix "nx," the plural is usally formed by changing the "x" ending to _____.

ges

e.g.  phalanx to phalanges

phalanx = a bone of the finger or toe

600

ex v. in

ex = out of, outside, away from

in = in, into, not, without

e.g. expiration

e.g intramuscular

600

ILEUM

ILIUM

ILEUM—the last and longest portion of the small intestine

ILIUM—part of the hip bone (tip i for the i in hip)

600

If the singular term ends in the suffix ends in "on," the plural is usually formed by changing the ending to an _______.

a

e.g. criteria becomes criterion

ganglia become ganglion 

ganglia =  (1) a structure containing several nerve cell bodies, typically linked by synapses, and often forming a swelling on a nerve fiber (2) a network of cells forming a nerve center in the nervous system of an invertebrate (3) a well-defined mass of gray matter within the central nervous system

700

macro v. micro 

macro—large, abnormal size, long

micro—small

e.g. macrocytosis— red blood cells are larger than normal, a lab finding that can point to something low vitamin B12 or folate, alcohol use, liver problems, certain medicines, or bone marrow issues.

e.g. microcyte—unusually small red blood cell



700

infection

inflammation

infection—invasion by a pathogenic organism. Although the suffix ITIS = inflammation, it is also commonly used to indicate infection. e.g meningitis mening refers to the meninges (three protective membranes that surround the brain and spinal cord) and the cause of the inflammation is the infection   

inflammation—response to injury or destruction of tissues. SIGNS: erytheme (redness) hyperthermia (heat) edema (swelling)

700

If the singular ends in the suffix "um," the plural is usually formed by changing the ending to _____.

a

example ovum to ova

ovum = egg

800

mega/megalo v. oligo

mega—large or great

oligo—scanty or few

e.g., megaloblast—large, abnormally large blood cell

e.g. oliguria—the production of small amounts of urine

800

laceration v. lesion

laceration—a torn or jagged wound or an accidental cut

lesion—a pathologic change of the tissues fue to disease or injury (lesions on the brain = cancer)

800

If the singular ends in the suffix "us," the plural is usually formed by changing the ending to _____.

"i"

e.g., alveolus to alveoli (any of the many tiny air sacs of the lungs which allow for rapid gaseous exchange)

e.g., malleolus to malleoli (a bony projection with a shape likened to a hammer head, especially each of those on either side of the ankle.)

900

pre v. post

pre—before

post—after

prenatal—before birth

post—postoperative

900

Mucous v. Mucus 

Mucous—specialized membranes that line the body cavities

Mucus—the fluid secreted by mucous membranes

900

ectomy

surgical removal 

e.g appendectomy—the surgical removal of the appendix (append = appendix; ectomy = surgical removal

1000

palpation v. palpitation

palpation—an examination technique in which the examiner's hands are used to feel the texture, size, consistency, and location of certain body parts.

palpitation—a pounding or racing heart

1000

ologist v ology

ologist—specialist such as a dermatologist (skin doctor)

ology—the study of such as NEONATOLOGY—the study of disorders of the newborn (neo=new; nat = birth; ology = study of

1000

ostomy

a surgical creation of an artificial opening to the body surface

e.g., colostomy—the surgical creation of an artificial excratory opening between the colon and the body surface (col = colon; ostomy = the surgical opening of an artificial opening.)

1100

malaise 

exudate

malaise—a feeling of general discomfort or uneasiness that is often the first sign of infection or disease 

exudate—any fluid such as pus that leaks out of an infected wound

1100

myelopathy v. myopathy

myelopathy—any injury, degeneration, or disease in the spinal cord (myel/o = spinal cord or bone marrow and pathy = disease)

myopathy—describes any pathologic change or disease of the muscle tissue (my/o=muscle and pathy =disease)

1100

otomy

cutting or surgical incision

e.g., pyelotomy = a surgical incision into the renal (kidneys) pelvis to remove obstructions such as kidney stones (pyel means renal pelvis, and otomy means surgical incision

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