Labs/ assessment
Serum Calcium
Which viatmin is essential for optimal absortbtion of calcium from the diet?
Vitamin D
What education should the nurse provide the client when taking Alendronate?
Sit upright and do not eat or drink for at least 30 minutes. Report difficulty swallowing.
What is one potential adverse effect that may be identified through lab monitoring during Denosumab therapy?
Hypocalcemia
Which of the following best describes a drug-drug interaction?
When two drugs are taken together and one alters the effect of the other.
Which of the following scenarios can significantly accelerate bone resorption, leading to osteoporosis? -Chronic use of corticosteroids -Premature ovarian failure -High dietary calcium intake - Hyperparathyroidism
-Chronic use of corticosteroids -premature ovarian failure -Hyperparathyroidism
What is the primary therapeutic action of denosumab in treating metabolic bone disease?
Inhibits osteoclast-medicated bone resorption
What is an important instruction for clients taking oral bisphosphonates?
Remain upright for at least 30 minutes after the dose.
What is a potential adverse effect of calcitonin therapy used for metabolic bone disease?
Nasal irrational or rhinitis
Select all situations that could increase the risk of drug interactions. (all that apply) -A patient taking multiple medications for chronic conditions -A patient not taking any other medications -A patient using both prescription and OTC medicines. -A patient eating a high-fiber diet. -A patient seeing multiple healthcare providers who are unaware of all medications.
-A patient taking multiple medications for chronic conditions.
-A patient using both prescription and OTC medicines.
-A patient is seeing multiple healthcare providers who are unaware of all medications.
Which lab value is most important to monitor in a client prescribed calcium supplements for osteoporosis?
Serum calcium
What is a major adverse effect associated with excessive calcium supplementation?
Hypercalcemia
A client is prescribes calcium citrate. What instructions should the nurse provide about taking the tablet?
Chew before swalllowing
Which adverse effect is commonly associated with bisphosphonate therapy for osteoporosis?
Esophageal irratation
Which medication used for osteoporosis may have its absorption impaired when taken with calcium supplements?
Which Clinical scenarios might prompt additional lab monitoring when using agents to treat metabolic bone disease? -Renal impairment -History of Cancer -Active infection -Well controlled hypertension -Seasonal Allergies
-Renal impairment
-History of cancer
-Active infection
Which medication is a selective estrogen receptor modulator (SERM) used for postmenopausal osteoporosis?
Raloxifene
Which of the following should a nurse include when educating a client about ways to prevent osteoporosis?
Increase physical activity, including weight-bearing exercises.
What is a serious but rare adverse effect of bisphosphonates, particularly after prolonged use?
Osteronecrosis of the jaw
A 68 y/o woman with osteoporosis is prescribed alendronate and is taking OTC calcium carbonate supplement (PPI) for GERD. What are the concerns with drug-drug interaction?
The PPI reduces the acid environment and calcium carbonate requires an acidic environment.
Which lab values may be monitored during treatment with antiresorptive agents for metabolic bone disease? -Serum calcium -BUN -Creatinine -Vitamin D levels -Parathyroid hormone
-Serum Calcium
-Vitamin D levels
-Parathyroid Hormone
Which medication is prescribes to inhibit bone resorption in osteoporosis management?
Alendronate
What is the primary physiological effect of decreased estrogen during menopause on bone health?
Increased bone resorption
A client receiving denosumab reports new-onset jaw pain. What lab-related explanation might be relevant?
Osteonecrosis risk and bone markers
A client prescribed a bisphosphonate is also taking NSAIDS daily. What risk should the nurse monitor for?
Increased risk of GI irritation or ulceration.