Statins
What is Headache and gastrointestinal side-effects
What famous basketball player is trending on TikTok right now for his AI medical explanations
LeBron James
Name a Second-line lipid-lowering agent
Fibrates, bile acid resins, niacin, and cholesterol absorption inhibitors
PCSK9 Inhibitors
Inhibition of PCSK9
What small organ is anterior to the right kidney?
The Gallbladder
Statins reduce BLANK BLANK synthesis by inhibiting enzyme HMG-CoA reductase.
What is hepatic cholesterol
During what game was the term "SUS" originally coined
Among Us
PCSK9 inhibitors are contraindicated in patients with what condition(s)
History of hypersensitivity
Bile acid sequestrants
Ion exchange resin binds bile acids in the intestine → interruption of enterohepatic circulation
(↓ bile acid absorption and ↑ bile acid excretion)
The falciform ligament is a remnant of what organ?
The Coronary Ligaments
Rosuvastatin, Atorvastatin and Pitavastatin
Which popular country artist was fined for throwing a chair off a 3 story roof last year?
Morgan Wallen
Second-line lipid-lowering agents are rarely indicated for what?
Primary Prevention of Cardiovascular Disease. They do not improve cardiovascular outcomes or mortality.
Statins
Competitive inhibition of HMG-CoA reductase
Name one of the two largest impressions on the liver
Gastric, Renal, colic
Statins should ideally be administered during what time of the day
Ideally administered in the evenings (especially simvastatin)
In a 2019 episode of "Game of Thrones," this musician portrayed a soldier who briefly shares a scene with Arya Stark, sparking mixed reactions from fans.
Who is Ed Sheeran
Bile acid sequestrants are indicated in patients with what condition and or what toxicity?
Hypercholesterolemia: combination therapy with statins
Digitoxin overdose
Ezetimibe
Selective inhibition of cholesterol reabsorption at the brush border of enterocytes
What makes the Caudate lobe vascularly unique
Receives blood from both right and left portal veins and drains directly into the IVC.
Name one High-Intensity Statin and one Moderate-intensity Statin
High-intensity statins lower LDL-C by ≥50% and include:
• Atorvastatin 40-80 mg
• Rosuvastatin 20-40 mg
Moderate-intensity statins lower LDL-C by 30-49% and include:
• Atorvastatin 10-20 mg
• Rosuvastatin 5-10 mg
• Simvastatin 20-40 mg
• Pravastatin 40-80 mg
• Lovastatin 40 mg
• Fluvastatin XL 80 mg
• Fluvastatin 40 mg BID
• Pitavastatin 1-4 mg
During what Oscar did Will Smith smack Chris Rock
94th Academy awards
According to Amboss, what is the one major statin medication contraindicated in Pregnancy?
Lomitapide
Lomitapide
Inhibits microsomal triglyceride transfer protein (MTTP)
Which artery typically runs within the boundaries of the Calot's triangle?
Cystic Artery?