used for its immune-modulating effects
what is rituximaub
halts the production of unnecessary antibodies and decreases dz activity; live vaccines contraindicated for 30 days prior
what is belimumab
used topically for cutaneous manifestations
what is corticosteroids
low oral doses vs high doses
what is minor dz activity vs major dz activity
patient education for corticosteroids
what is taken w food, get yearly flu vaccine, and do not abruptly stop or life-threatening complications may occur
hepatoxicity - elevated LFTs
increased risk of retinal toxicity or retinopathy
what is hydroxychloroquine
often used in conjunction w corticos - minimize corticosteroid requirements
what is NSAIDs
reserved for pts who have serious forms of SLE that haven't responded to conservative therapies; examples; safety considerations
what is immunosuppressive agents; cyclophosphamide, azathioprine, mycophenolic acid, and methotrexate; contraindicated in pregnancy and most used in SLE nephritis
A patient has been prescribed long-term corticosteroid use. The nurse educates the patient that they will need bone mineral density tests performed when?
what is at diagnosis and prior to beginning steroid use and then q2years thereafter
A nurse understands that a patient with lupus needs to be receiving supplements. Which two should the nurse recommend to the patient?
what is calcium and vitamin D
biologic response modifiers function and examples
what is stimulates the growth of WBCs; Neulasta, pegfilgrastim, filgrastim
the immune suppressants _____________, ___________, and __________ are usually needed in higher doses for children
what is azathioprine, cyclosporine, and tacrolimus
what is immunosuppressive therapy medications suppresses platelet formation
A nurse is educating a patient on the use of immunosuppressive therapy medications for the prevention of transplant rejection. Which of the following risks are associated with these medications? SATA.
a. nephrotoxicity
b. hypotension
c. hyperlipidemia
d. hirsutism
e. cataracts
f. gingival hyperplasia
what is A, C, D, E, F
A patient has just been brought into the ER after an apparent alcohol overdose. The nurse plans to begin the process of safe withdrawal. Which medication(s), if any 🤪, would the nurse plan to administer to this client? SATA.
a. lorazepam
b. tacrolimus
c. disulfiram
d. chlordiazepoxide
e. diazepam
f. cyanocobalamin
what is A, D, E
antipsychotic, controls hallucinations, lowers BP, and relieves nausea
what is chlorpromazine
given every few hours until opioid level drops to nontoxic
whats is naloxone
cyanocobalamin
what is B12
phencyclidine overdose medications purpose
what is control BP and seizures
disulfiram client education
what is read labels to avoid products with alcohol
levomethadyl patient education
buprenorphine/naloxone
what is may cause OH, sedation; avoid CNS depressants; maintains abstinence from opioids and ↓ opiate cravings
naltrexone
what is may not respond to narcotics used to tx cough, diarrhea, or pain; take w food or milk; may cause headache, restlessness, and irritability; blocks effects of opiates; decreases alcohol cravings
acamprosate: monitor for?
what is diarrhea, vomiting, flatulence, and pruritis; suppresses alcohol cravings
urine may be dark yellow
what is folic acid