Misc.
Norepinephrine is ________ in depression.
What is decreased?
This is the mechanism by which SSRIs and SNRIs exert their effects.
What is blocking the reuptake of serotonin and norepinephrine by the prep synaptic neuron?
MAOI stands for this.
What is Monoamine Oxidase Inhibitors?
These are the 2 main categories of typical antipsychotics.
What are the phenothiazines and nonphenothiazines?
Any drug that reduces this, may be described as an anxiolytic.
What is anxiety?
Benzodiazepines (BNZs) and benzodiazepine agonists are two main categories prescribed for this.
What is sleep?
Patients may not see the effects of SSRIs and SNRIs for _____ weeks after starting treatment.
What is 4-8 weeks?
Beer, sour cream, bananas, avocados, salami, chocolate and caffeinated drinks are some examples of foods/drinks high in this _______; these can cause serious interactions with MAOIs.
What is Tyramine?
Symptoms of psychosis are classified as _____ or _______.
What is positive or negative?
Early signs of _______ toxicity include, increased nausea, vomiting, drowsiness, muscle weakness, coarse hand tremors, and incoordination.
What is lithium?
These can be signs/symptoms of serotonin syndrome.
(name 3)
What is: confusion, agitation, restlessness, stomach disturbances, diarrhea, sweating, hypertension, seizures, dilated pupils, and tremors?
When a person abruptly stops their SSRI or SNRI they may develop anxiety, flu like symptoms, unease and depression. This is called ____.
What is discontinuation (withdrawal) syndrome?
Diabetics who take insulin or other anti diabetic drugs are at increased risk of this when taking MAOIs.
What is hypoglycemia?
The main adverse effects of typical antipsychotics are described as DIMDs, which stands for this. Bonus 50 points if you can name 1 of the 4 types.
What are drug induced movement disorders?
pseudoparkinsonism, acute dystonia, aka this is and Cardiff dyskinesia.
Abnormal or excessive elation, decreased need for sleep, grandiose notions, markedly increased energy and radical thoughts are some symptoms of this.
What is mania?
Antidepressants are able to cross this/these barrier(s).
What is the blood-brain and Placental-brain barriers?
Patients taking SNRIs should avoid this herb, as it may increase serotonin levels and potentially cause serotonin syndrome.
What is St. Johns Wort?
Do not give MAOIs and SSRIs within ______ weeks of each other. This my cause serotonin syndrome.
What is 2?
These drugs affect dopamine and serotonin receptors slightly differently from other atypical antipsychotics, as a result the have fewer motor side effects and adverse reactions.
What are dopamine system stabilizers?
The precise action of this category of drugs is unknown, but it thought to interfere with the reuptake of norepinephrine and serotonin.
What are tricyclic antidepressants (TCAs)?
These drugs are used primarily to treat patients with bipolar illness.
What are mood stabilizers?
Thids SSRI is commonly known as the "baby blues drug" due to its frequent use in treating postpartum depression.
What is Zoloft (sertraline)?
Name 2 side effects and 1 adverse effects of MAOIs.
What are: side- constipation, HA, dizziness, drowsiness and dry mouth.
Adverse liver damage, blood disorders and thoughts of suicide.
These have a lower risk of EPSs and have the benefit of treating negative and positive symptoms. (They are also more common for long-term management.)
What are atypical antipsychotics?
TCAs should not be used in patients with ________, as it can increase intraocular pressure.
What is glaucome?