Unit 1 The Infection
What is the collection, classification, storage, and analysis of biological information using computers?
BIOINFORMATICS
The process of inserting a functional gene into a person’s genome to replace a faulty gene is known as:
Gene therapy
A gene that has become cancerous is called this
Oncogene
What blood type agglutinates in anti-B?
Type B
Which antibiotic prevents DNA replication?
Fluoroquinolones
Disease samples from two patients were collected and subjected to serial dilutions before running an ELISA. What does it mean if the disease can be detected in samples from one person at a dilution of 1/5 but the disease can be detected in the other patient at a dilution of 1/5 and 1/100?
Both patients have the disease but the second patient has a stronger infection
Which procedure detects genetic disorders and chromosomal abnormalities and is usually performed between 10-13 weeks of pregnancy?
Chorionic villi sampling
A patient’s SNP profile correlates with his or her ability to tolerate chemotherapy with azathioprine. How do SNP profiles aid in pharmacogenetics?
It allows doctors to predict how a patient will react to a particular drug
Patient One has a panel reactive antibody screening of 25 and patient two has a panel reactive antibody screening of 59. Which patient has the better chance of the transplant?
Patient One
Difference between sensorineural and conductive hearing loss
Sensorineural affects the inner ear while conductive affects the outer and middle ear
List the steps of ELISA in order
Antigen, primary antibody, secondary antibody, enzyme, substrate
What is the role of PCR and which step of PCR involves Taq polymerase adding free nucleotides to the primer?
To make copies of DNA and annealing
Which type of clinical trial provides the most reliable results?
Double blind study because neither patients nor doctors know who is receiving the actual treatment
The name of the surgical procedure using trocars that removes the barrier of physical hands during transplant procedures.
Laparoscopy
During the ELISA test, the secondary antibody was conjugated (linked) with an enzyme. What happens when that enzyme comes in contact with a substrate?
The substrate causes the enzyme to oxidize resulting in a color change
Which type of genetic disorders are "good" candidates for gene therapy?
Single gene disorders
List one pro and one con of MRIs.
Pro- no radiation
Con- confined spaces / no metal
Name four medical professionals on a transplant team.
Surgeon
perioperative nurse
anesthesiologist
pharmacist
LIST the ABCDE of skin cancer.
asymmetry, borders, color, diameter, evolving
A 4 ml sample is put into a tube that has 60 ml of diluent, what will be the tube dilution?
1/16
Vaccine made from specific pieces of the pathogen, ie. protein or capsid
Subunit
List three functions of p53?
Halt cell cycle
Apoptosis
DNA repair
Which process gene transfer involves a bacteriophage?
Transduction