Gram-atic much?
Get in shape!
Specialized Structures
I'm moving out!
The Penicillin is mightier than the sword.
100

It is the primary stain used in the Gram stain procedure that turns all bacterial cells purple.

crystal violet

100

This term for a spherical bacterial shape shares its root with a word meaning "berry."

coccus/cocci

100

This non-membrane-bound region houses the densely packed, supercoiled bacterial chromosome.

the nucleoid

100

This broad category of transport moves molecules against their concentration gradient and strictly requires cellular energy.

active transport

100

This type of antibiotic, like penicillin, targets the cross-linking of the peptidoglycan layer to cause cell lysis. 

beta-lactam antibiotics

200

These barrel-shaped outer membrane proteins allow the passive diffusion of small hydrophilic molecules in Gram-negative bacteria.

porins

200

Counterclockwise rotation of bundled bacterial flagella results in this smooth, linear movement.

a run

200

These elongated protein appendages facilitate bacterial conjugation and a jerky surface movement known as twitching motility.

Pili

200

These specialized channel proteins facilitate the rapid, passive diffusion of water across the cell membrane.

aquaporins

200

Polymyxin antibiotics interact with lipopolysaccharides (LPS), making them exclusively effective against this broad classification of bacteria.

Gram negative bacteria

300

This thick, heavily cross-linked layer protects Gram-positive cells from osmotic lysis.

peptidoglycan

300

This prokaryotic homolog of tubulin polymerizes to form the Z-ring, directing cell division.

FtsZ

300

Severe nutrient limitation triggers the formation of these highly resistant, dormant bacterial structures.

Endospores

300

Bacteria secrete these high-affinity, low-molecular-weight compounds to scavenge insoluble Fe3+ from the environment.

siderophores

300

Antibiotics that act as ionophores collapse this specific electrochemical gradient, completely removing the energy source for flagellar rotation.

proton motive force

400

Missing this specific chemical step in the Gram stain causes Gram-positive cells to wash out and falsely appear pink.

mordant step / iodine

400

This actin homolog maintains the rod shape of bacilli by acting as a track for localized cell wall synthesis.

MreB

400

Complexed with calcium, this chemical compound in the spore core protects DNA by replacing water and preventing heat denaturation.

DPA

400

ABC transporters derive their energy from this chemical reaction.

ATP hydrolysis

400

A newly developed drug that selectively targets the FtsZ protein would primarily disrupt this critical cellular process.

Cell division

500

This tightly packed, organized polysaccharide layer is firmly attached to the cell and protects against phagocytosis.

capsule

500

A loss-of-function mutation in this specific phosphatase results in continuous tumbling.

CheZ

500

During sporulation, SpoIIE activates this specific transcription factor exclusively in the forespore compartment.

Sigma F

500

Exclusive to Gram-negative bacteria, this specialized transport system harnesses the proton motive force to move scarce molecules across the outer membrane.

TonB-dependent transport

500

This Gram-negative structure provides intrinsic resistance to large, bulky antibiotics like vancomycin.

the outer membrane

M
e
n
u