Materials
Background Concepts
Polymers + CS/JD
Biological Responses
100

Of the five electromagnetic forces, “chemical crosslinks” generally refer to this type of bond in biomaterials

Covalent bonding

100

This is the process of a materials integrating itself with bone

Osseointegration

100

This describes the homogeneity of the molecular weight of a polymer batch

Polydispersity

100

These unique cells are typically the next-stage evolution of overly-frustrated macrophages

Foreign Body giant cell

200

Rather than measuring the force and stress normal to the cross section of the material, this is dependent on the force vector parallel to the cross section of a sample

Shear stress

200

Despite its inflammatory-like name, this is the body's natural response to an implanted biomaterial.

Foreign Body Reaction

200

A crystalline polymer brought above it’s crystalline melt point is reverted back to this state

Amorphous

200

These “first responders” of the immune system are known for their multi-lobed nuclei

Neutrophils

300

Stress is the intrinsic version of this extrinsic vector quantity

Force

300

In contrast to apoptosis, this form of cell death typically leads to inflammatory reactions by the immune system

Necrosis

300

The Cordis Cypher stent infamously caused this type of adverse reaction

Thrombosis

300

Cells undergoing necrosis are likely to release these, initiating an inflammatory reaction

DAMPS

400

This is the amount of stress a material can withstand before undergoing permanent deformation

Yield Strength

400

This type of cell study involves complex mixtures of adhesive proteins with or without ones removed, and is a more realistic way to determine adhesion actors in vivo

Depletion study

400

To describe how susceptible patients were to certain ailments and diseases after receiving breast implants compared to non-patients, the NEJoM articles used this metric

Relative Risk

400

The formation of this bacterial ECM-like substance can prevent the efficicacy of antibiotic treatment

Biofilm

500

This test subjects samples to a fixed load, while measuring the variable strain that changes over time under that load

Creep Test

500

Stems cells have two defining traits: self-renewal, and this

Differentiation

500

Crystallinity in polymers is known to prevent this, one of two primary polymer degradation pathways

Hydrolysis

500

These are three components that activate platelets

Thromboxane, ADP, and thrombin

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