Drug Therapy Across the Lifespan
DURING WHAT TRIMESTER IS A PREGNANT WOMAN MOST AT RISK FOR ADVERSE DRUG REACTIONS WITH POTENTIAL LONG-TERM CONSEQUENCES?
During the 1st trimester, the fetus is at most risk due to the occurrence of rapid growth
What class of medications are used to treat hypertension?
Diuretics, BB, CCB, Inhibitors of the Renin-Angiotensin-Aldosterone System
What drug schedule can not be prescribed by a Nurse Practitioner?
Schedule 1
What Joints are commonly affected in Osteoarthritis?
Hands (DIPs), large weight-bearing joins (hips, knees)
What is Full-Practice Authority?
Nurse practitioners have the autonomy to evaluate patients, diagnose, order and interpret tests, initiate and manage treatments and prescribe medications, including controlled substances without physician oversight.
What are some medications that should be avoided in pediatric patients?
glucocorticoids, discoloration of developing teeth with tetracyclines, and kernicterus with sulfonamides
What is typically the first-line treatment in an African American patient after a thiazide diuretic?
Calcium Channel Blocker (CCB)
What are strong opioid analgesics usually reserved for?
moderate to severe pain. The drug can relieve postoperative pain, pain of labor and delivery, and chronic pain caused by cancer and other conditions.
Which lab value would we expect to see elevated in Rheumatoid Arthritis?
ESR
What is restricted Practice Authority?
Nurse practitioners are limited in at least one element of practice by requiring supervision, delegation, or team management by an outside health discipline for the nurse practitioner to provide patient care.
Why do Nitrates need to be taken no later than 4 pm?
Need nitrate free interval so tolerance doesn’t develop
What is the basic MOA of most diuretics?
blockade of sodium and chloride reabsorption.
When Prescribing Opioids, should a patient be started on IR or ER?
IR
What diet should a patient with Gout follow?
Low- Purine Diet
What/who is scope of practice determined by?
Nurse practitioner's scope of practice is determined by state practice and licensure laws.
What are some medications that we know to be teratogenic?
Antiepileptic drugs, antimicrobials such as tetracyclines and fluoroquinolones (pronounced fluoro-quino-lones) , vitamin A in large doses, some anticoagulants, and hormonal medications such as diethylstilbestrol (DES) pronounced di-ethyl-stil-best_rol.
What is the MOA of ACEI?
(1) reducing levels of angiotensin II (through inhibition of ACE) and (2) increasing levels of bradykinin (through inhibition of kinase II).
What is the typical dose of Nasal Naloxone and how is it administered?
4 mg; When using Narcan Nasal Spray, one spray is administered to one nostril, delivering 4 mg of naloxone. If there is no response, additional doses may be given every 2 to 3 minutes until emergency medical services arrive.
What is the most common fracture seen in Severe Osteoporosis?
Hip and Vertebrae
Who regulates prescription authority?
The regulation of prescriptive authority is under the jurisdiction of a health professional board. This may be the State Board of Nursing, the State Board of Medicine, or the State Board of Pharmacy, as determined by each state.
What is the importance of the BEERS criteria
PIM use in older adults due to medication-disease or medication-syndrome interactions that may exacerbate the disease or syndrome
What Medications should be used cautiously with Statins because they can raise plasma levels?
inhibitors of CYP3A4
What Drug Classification is Morphine?
Agonist- Antagonist Opioid
What dose of colchicine should a patient take during an acute gout attack?
1.2 mg orally initially, followed by 0.6 mg orally after 1 hour
What is the difference between NP practice authority and prescriptive authority?
Practice authority refers to the nurse practitioner's ability to practice without physician oversight, whereas prescriptive authority refers to the nurse practitioner's authority to prescribe medications independently and without limitations.