Topic 4
Stretches of conserved gene order in chromosomes is known as what?
What is a synteny
The two most frequent spontaneous chemical reactions known t o create serious DNA damage are depurination and …
What is deamination
RNA polymerase I transcribes genes 5.8s, 18S and ____
what is 28S rRNA
Proteins destined for extracellular functions are made by ____ ribosomes.
What are ER Ribosomes
Often occurring from errors in chromosome joining that lead to an area of euchrimatin being positioned in an area of heterochrimatin and silenced
What is the position effect
The enzyme that synthesizes short rna primers on the lagging strand
What is primase
What is a transcription essential that defines where transcription starts?
What is a DNA promoter
enzyme for transcribing rRNA in eukaryotes
RNA polymerase I
____ forms at the centromere and attaches the duplicated chromosomes to the mitotic spindle
What is the kinetochore
What are pieces of DNA that are transient components of lagging strand DNA synthesis at the replication fork?
What are Okazaki fragments
part of bacterial rna polymerase that recognizes and attaches to the promoter
What is sigma factor
Proteasomal degradation may proceed due to what form of ubiquitylation?
What is polyubiquitylation
These proteins recognize and bind specific DNA sequences in the chromosomes and determine where and when the chromatin-modifying enzymes will act
What are Transcription Factors
This enzyme produces a single strand break in front of the replication fork to relieve the double-helix of tension being built up by the replication fork
What is Topoisomerase I
The collection of RNA molecules and proteins that together form the structure responsible for removing introns from Pre-mRNA
What is the Spliceosome
chaperone ____ prevent incorrect folding by binding to proteins and helping stabilize the polypeptide chain
What is protein
A portion of the human genome contains ancient repetitive sequences known as:
What are transposons
Initiation of DNA replication in the bacterial genome can occur when the origin is
What is full methylation
The 2’ hydroxyl group of RNA allows this type of reaction to occur during splicing
What is hydrolysis
This is the region of a tRNA molecule that recognizes the 3-nucleotide sequence that indicates which amino acid should be added to the 3’ end of the tRNA in the production of a protein
What is an Anti-Codon