Cellular respiration
The first step in cellular respiration
What is glycolysis?
What is adenosine triphosphate?
Mutations in genes with a primary link to the dunction of the electron transport chain.
The process by which the energy stored in a proton gradient is used to drive cellular work
What is chemiosmosis?
The theory describing the engulfment of oxygen-breathing bacteria by a eukaryotic cell to eventually form the mitochondria
What is endosymbiosis?
The study of the complete set of RNA transcripts produced by the genome.
Transcriptomics
2 pyruvate, 2 ATP, 2 NADH and 2H2O
What are the end products of glycolysis?
A mitochondrial outer membrane translocator that allows nuclear proteins to enter
What is TOM?
A combination of vitamins designed to optimise mito patients' nutrition and health to prevent worsening of symptims
What is a mito cocktail?
An enzyme that plays a role in the citric acid cycle and the electron transport chain.
What is complex II?
What is heteroplasmy?
A measure of the enzyme activity of mitochondrial complexes to determine their function, helping to diagnose mitochondrial disease.
What is a respiratory chain enzymology assay?
An electron transport chain complex that accepts an electron from ubiquinone
What is complex III?
37 genes in human cells: 2 rRNA, 22 tRNA and 13 proteins
What are the genes encoded by the mitochondrial genome?
A mitochondrial disease caused by mutations in MT-TL1, causing encephalomathy, lactic acidosis and stroke like episodes.
What is MELAS?