Hired guns
The class of antibiotics that penicillin belongs to
What is beta-lactam?
The McFarland standard used for preparing inoculum for AST
What is 0.5 McFarland?
The minimum concentration of antibiotic required to inhibit the growth of a particular organism
What is Minimum Inhibitory Concentration/MIC?
The term for a combination of antimicrobial agents that have antibacterial activity significantly greater than that of the single agents
What is synergism?
The mechanism of action for beta-lactams and glycopeptides
What is inhibit cell wall synthesis?
Streaking method used for a disk diffusion test
What is lawn?
When measuring zones of inhibition for a disk diffusion test, CLSI guidelines are used to determine whether an organism is one of these three possible interpretations to a particular antibiotic
What is susceptible, intermediate or resistant?
Most all Staphylococcus are resistant to this antibiotic due to the activity of beta-lactamase
What is penicillin?
The mechanism of action for aminoglycosides, tetracyclines and macrolides
What is inhibit protein synthesis?
AST method involving disks impregnated with antibiotics and the reading of zones of inhibition to determine susceptibility
What is Kirby-Bauer?
Consequence of setting up a disk diffusion AST with more than 12 disks on a 150mm plate
What is overlapping zones of inhibition that cannot be measured?
The antibiotic recommended by CLSI for the detection of oxacillin resistance in Staphylococcus
What is cefoxitin?
The mechanism of action for fluoroquinolones
What is inhibit nucleic acid synthesis?
AST method that involves using a plastic strip impregnated with a gradient of antibiotic that produces an elliptical zone of growth to determine susceptibility
What is an E-test?
Consequence of setting up a disk diffusion AST with an inoculum that was too heavy
What is false resistance?
The production of beta-lactamase is detected by using a disk impregnated with this
What is nitrocefin?
The mechanism of action for sulfonomides
What is inhibit folate biosynthesis?
Media used for disk diffusion testing
What is Mueller-Hinton?
Consequence of setting up a disk diffusion AST with agar that is too thin?
What is false susceptibility?
The test used to detect inducible clindamycin resistance
What is the D test?