Germans love to use baker's yeast for this beverage
What is beer?
The two gender types in worms
What are males and hermaphrodites
Number of chromosomes in the fly
What is four?
Know the phenotype. Don’t know gene responsible
What is a forward genetic screen?
An allele with a partial loss of function
What is a hypomorphic allele?
This plasmid is lost after 5FOA treatment
What is the URA3 plasmid?
Test cross of two dumpy worm strains that results in wild type offspring
What is a Cis Trans Test? (Complementation, Two different genes)
Diet of a fruit fly
What is yeast?
Large scale morpholino screen to study startle response pathway
What is a reverse genetic screen?
Sleep involves many genes and environmental factors
What is a complex trait?
Prey and bait to study interactors
What is two hybrid?
Specialized larval stage for enduring adverse conditions
What is dauer
The phenotype for UAS-GFP; Gal4
What is GFP positive
Sequence-specific nuclease used to generate gene knock outs
What is CRISPR/Cas 9 (Zinc-finger nucleases (ZFNs), TALENs)?
Upon Cre expression, gut cells get randomly and stably labeled with one of the four colors
What is the Confetti Mouse
Mutant strain dies at 37˚C and is wild type at 25˚C
What is temperature sensitive?
Typical brood size for C. elegans
What is 300
Genetic tool allows lethal mutations to be maintained without selection
What are balancer chromosomes?
Equipment crucial for this technique
What is breeding and egg collection (microinjection)?
Genetic engineering technique that inserts a specific gene sequence into a target organism's genome.
What is a"knock-in" mouse model?
Human RNF4 rescues the yeast slx5∆ mutant phenotype
What is cross complementation?
Germ cells in distal arm of gonad do not have cell membranes (so ideal place to inject DNA).
What is the syncitial region.
Embryonic lethal genes can be studied by creating mitotic clones in any cell or tissue.
What is FRT/FLP Recombination Technology?
Zebrafish are fresh water fish native to this area
What is South Asia? (Napal, India, etc)
Inject human cells into a immunocompromised (NOD scid) mouse
What is a xenograft (PDX) model?