How many rights of medication administration are there?
What is an adverse drug event?
Any undesirable occurrence related to administering or failing to administer a prescribed medication.
What is the difference between generic name and trade name?
Generic-Name given by the United States Adopted Names Council
Trade-Manufacturer name
What is the normal pH of the blood?
7.35-7.45
Neonates and children have greater ______ and less ______.
total body water and fat
Giving your patient their medication 1 hour after a meal due to a food-drug reaction, observes which right?
Right Time.
What is the definition of an agonist?
A drug that binds to and stimulates that activity of one or more receptors in the body.
What are the 4 principles of pharmacokinetics?
Absorption, Distribution, Metabolism and Excretion
What are the normal levels of albumin in the blood?
3.4-5.4
Which two systems are affected by immaturity in neonates and children?
Liver and Kidneys
Right to refuse is the 9th right, what actions will you take if your patient refuses a medication?
Educate patient on the rationale for the medication, document the refusal and notify the provider.
What is the definition of an antagonist?
A drug that binds to and inhibits the activity of one or more receptors in the body. (Also known as inhibitors)
Where is the major site of metabolism for drugs?
Liver
What labs will allow you to assess liver function?
AST, ALT, Bilirubin, Total Protein
Accurate ______ is important when checking medication dosage in children and neonates.
weight
Benadryl 25-50mg PO every 8 hours as needed for blood transfusions.
Which right prevents you from giving this medication?
Right Reason/Indication
What is the definition of biotransformation?
One or more biological reactions involving a parent drug. (Also known as metabolism)
What is the difference between hydrophilic and lipophilic?
Hydrophilic-water loving, lipophilic- fat loving.
? is the process that your kidneys use to filter excess fluid and waste products out of the blood into the urine collecting tubules of the kidney, so they may be eliminated from your body.
Glomerular Filtration
Due to decreased organ function, older adults are at higher risk for______.
Drug Toxicity
Right Reason/Indication, Right Time and Right to Refuse, what are the remaining rights?
What is a drug interaction?
Changes in the way one drug works in the presence of one or more other drugs.
Which organ is primarily responsible for excretion?
Kidney
What conditions can affect the integrity of the blood brain barrier?
Trauma, Hypertension, Infection, Radiation
Older adults are more at risk for complications and medication errors due to _______.
Polypharmacy.