Immunity and Inflammation
Infection
Tissue Integrity
Stress and Coping
Mood and Affect
100

A nurse is assessing a patient with a minor skin injury and notes localized redness and warmth at the site. The nurse understands that this "erythema" is primarily caused by which process?

A. The formation of a fibrin wall

B. Increased blood flow (hyperemia) to the area

C. The migration of lymphocytes to the site

D. A systemic febrile response

B: Erythema (redness) is a local manifestation of inflammation caused by hyperemia, which is increased blood flow to the injured area. 

100

A nurse is teaching a student about the different types of pathogens. Which of the following is an example of a fungal infection? 

A. Staphylococcus aureus 

B. COVID-19 

C. Tinea pedis 

D. Malaria

C: Tinea pedis (athlete's foot) is a specific example of a fungal pathogen, which includes yeasts, molds, and mushrooms. 

100

A nurse is reviewing the anatomy of the skin with a group of students. Which layer of the skin is described as the innermost layer containing fat cells that assist with temperature regulation and cushioning? 

A. Epidermis 

B. Dermis 

C. Subcutaneous tissue (hypodermis) 

D. Epithelial barrier

C: The subcutaneous tissue (or hypodermis) is the innermost layer and is responsible for cushioning and temperature regulation. 

100

A patient is describing a new job as a "major threat" to their financial stability. The nurse recognizes that the patient’s interpretation of this stressor is known as: 

A. Allostasis 

B. Homeostasis 

C. Stress Appraisal 

D. Sense of Coherence

C: Stress appraisal is defined as how a person interprets or evaluates a stressor as a threat, challenge, or harmless. 

100

A nurse is documenting a patient's emotional state. The patient reports feeling "down in the dumps" for the past two weeks, but the nurse observes the patient smiling and laughing while talking with family. How should the nurse correctly define the patient's smiling and laughing? 

A. Mood 

B. Affect 

C. Functional ability 

D. Allostasis

B: Affect is defined as the outward expression of emotion that others can observe, such as facial expressions, whereas mood is the long-lasting internal emotional state. 

200

A mother asks the nurse why her newborn is protected from certain infections shortly after birth. The nurse explains that some antibodies were passed from the mother to the fetus through the placenta. This is an example of: 

A. Innate immunity

B. Active acquired immunity

C. Passive acquired immunity

D. Cell-mediated immunity

C: Passive acquired immunity occurs naturally when antibodies pass from a mother to a fetus via the placenta. 

200

In the chain of infection, a nurse identifies a blood pressure cuff used on multiple patients as a place where pathogens can live and grow. This cuff represents which link in the chain? 

A. Portal of Exit 

B. Source of Infection (Reservoir) 

C. Susceptible Host 

D. Portal of Entry

B: The Source of Infection (Reservoir) is defined as where a pathogen lives and grows, including inanimate objects like medical equipment. 

200

A nurse is performing a daily assessment on a medical-surgical unit. Using the Braden Scale for Predicting Pressure Sore Risk, which total score would indicate that a patient is considered "at risk"? 

A. 23 

B. 20 

C. 19 

D. 16

D: On the Braden Scale, a score of less than 18 (out of 23) generally indicates the patient is at risk for pressure injuries. 

200

A nurse is assessing a patient in the "Alarm Stage" of the General Adaptation Syndrome (GAS). Which physiological findings should the nurse expect? 

A. Decreased blood pressure and lethargy 

B. Increased heart rate and rapid breathing 

C. Stabilized vital signs and muscle relaxation 

D. Depleted energy levels and chronic illness

B: During the alarm stage, the body activates the fight-or-flight response, leading to increased heart rate, blood pressure, and alertness. 

200

A nurse is providing education to a new mother about infant development. The nurse explains that for an infant, emotional regulation begins through which process? 

A. Developing abstract thinking and identity formation 

B. Internalizing socially acceptable ways to manage feelings 

C. Caregiver interaction and forming trust/attachment 

D. Drawing on life experiences to manage daily stressors

C: In infants, emotional regulation begins through caregiver interaction, which forms the trust and attachment necessary for later emotional control. 

300

A patient presents to the clinic with symptoms of a severe seasonal allergy, including sneezing and watery eyes. Which immunoglobulin (antibody) is primarily responsible for triggering these allergic symptoms? 

A. IgG 

B. IgA 

C. IgM 

D. IgE


D: IgE is the antibody responsible for triggering allergic symptoms and fighting parasites. 

300

A patient is admitted to the medical-surgical unit with a suspected diagnosis of Tuberculosis (TB). Which transmission-based precautions must the nurse implement? 

A. Contact Precautions 

B. Droplet Precautions 

C. Airborne Precautions 

D. Standard Precautions only

C: Airborne Precautions are required for pathogens like TB, measles, and chickenpox, which are spread by tiny particles that stay in the air. 

300

During a skin assessment of an immobile patient, the nurse observes a localized area of nonblanchable redness over the coccyx. The skin remains intact, but the area feels firmer and warmer than the surrounding tissue. How should the nurse stage this pressure injury? 

A. Stage 1 

B. Stage 2 

C. Stage 3 

D. Unstageable

A: Stage 1 pressure injuries are characterized by intact skin with nonblanchable erythema (redness); changes in sensation or firmness may also be present. 

300

A client who recently lost their job tells the nurse, "I have started a daily exercise routine and joined a professional networking group to find new opportunities." The nurse identifies these as which type of coping? 

A. Emotion-focused coping 

B. Meaning-focused coping 

C. Problem-focused coping 

D. Maladaptive coping

C: Problem-focused coping involves taking direct action to solve a problem, such as making a plan or seeking help. 

300

During a mental status assessment, the nurse asks a patient, "What would you do if you found a stamped, addressed envelope lying on the sidewalk?" Which component of the assessment is the nurse evaluating? 

A. Orientation to person, place, and time 

B. Judgment and insight 

C. Perception and cognition 

D. Affective instability

B: A mental status assessment includes evaluating a patient’s judgment and insight, along with orientation, memory, and thought processes. 

400

A patient undergoing chemotherapy for cancer is found to have a significantly decreased white blood cell count and a failure of the normal immune response. How should the nurse document this condition? 

A. Primary immunodeficiency 

B. Secondary immunodeficiency 

C. Autoimmune disease 

D. Optimal immune response

B: Secondary immunodeficiency refers to a loss of immune function resulting from an external factor, such as chemotherapy or illness. 

400

A nurse is performing a screening for a sexually active female patient and explains that a Pap smear is used to detect the presence of Human Papillomavirus (HPV). This is an example of which level of prevention? 

A. Primary Prevention 

B. Secondary Prevention 

C. Tertiary Prevention 

D. Collaborative Intervention

B: Secondary prevention involves screening for the identification of pathogens, such as using Pap smears to screen for HPV in sexually active women. 

400

A nurse is assessing a patient's abdominal wound four days after surgery. The nurse notes the formation of new vascular networks and collagen structures, giving the wound a pink, vascular appearance. The nurse correctly identifies the wound is in which phase of healing? 

A. Inflammatory Phase 

B. Granulation Phase 

C. Maturation Phase 

D. Remodeling Phase

B: The Granulation Phase is characterized by the creation of new vascular networks and collagen, giving the wound a pink, vascular appearance. 

400

A school nurse is assessing a 7-year-old child who has been experiencing significant stress due to changes at home. Which clinical manifestation is most characteristic of a child's stress response? 

A. Verbalizing a need for career transitions 

B. Physical symptoms such as stomachaches or headaches 

C. Increased use of complex problem-focused coping 

D. Development of chronic hypertension and vascular failure

B: Children often manifest stress through physical symptoms like stomachaches, headaches, or behavioral changes such as irritability. 

400

A community health nurse is organizing a depression screening event at a local senior center. This initiative is an example of which level of prevention? 

A. Primary prevention 

B. Secondary prevention 

C. Tertiary prevention 

D. Collaborative intervention

B: Secondary prevention involves early detection and intervention, such as screening for depression or anxiety, to prevent the progression of a mood disorder. 

500

A nurse is reviewing the laboratory results for a patient with suspected systemic inflammation. The results show an elevated C-reactive protein (CRP) and an increased Erythrocyte Sedimentation Rate (ESR). Which interpretation of these findings is most accurate? 

A. The patient has a specific bacterial infection in the lungs 

B. The patient’s body is failing to produce fibrinogen 

C. These are non-specific markers confirming the presence of an active inflammatory process 

D. The patient is experiencing a suppressed immune response

C: Both CRP and ESR are non-specific markers; they confirm inflammation is present in the body but do not identify the exact cause or location. 

500

When a bacterial invasion occurs, which component of the immune response is specifically responsible for differentiating into plasma cells to produce antibodies and creating memory cells for future exposures? 

A. T Lymphocytes 

B. B Lymphocytes 

C. Macrophages 

D. The Complement System

B: B Lymphocytes are activated during bacterial invasion to differentiate into plasma cells (which produce antibodies) and memory cells. 

500

A nurse is caring for a patient with a deep pressure injury on the heel that is completely covered by thick, tan-colored slough and black eschar. Which statement best describes the nurse's priority for this wound? 

A. Stage the wound as a Stage 4 pressure injury immediately. 

B. Recognize the wound is unstageable until debridement is performed. 

C. Apply a dry dressing to encourage the eschar to fall off naturally. 

D. Document the wound as a partial-thickness skin loss.

B: A wound is unstageable if the depth of tissue damage is obscured by slough or eschar. The true stage (usually 3 or 4) cannot be determined until debridement occurs. 

500

The nurse is caring for a patient who has been experiencing prolonged, chronic stress for several years. The nurse understands that the constant release of cortisol and adrenaline in this patient will most likely result in: 

A. A return to a stress-neutral state 

B. Enhanced immune system functioning 

C. Weakened immunity and increased susceptibility to illness 

D. Immediate resolution of the fight-or-flight response

C: Prolonged or chronic stress leads to constant activation of the sympathetic nervous system and high levels of cortisol, which causes weakened immunity and physical exhaustion. 

500

A nurse is caring for a patient who has expressed clear suicidal ideation. According to nursing standards for mood and affect, what is the nurse's immediate priority? 

A. Educate the family on the warning signs of suicide. 

B. Use motivational interviewing to explore the patient's feelings. 

C. Ensure patient safety by maintaining close observation and removing harmful means. 

D. Coordinate a meeting with the interprofessional team to discuss medication.

C: For a suicidal client, the nurse’s role is to ensure safety first. This includes performing a risk assessment, maintaining close observation, and removing potential means of self-harm. 

600

A patient suddenly develops a life-threatening systemic allergic reaction (anaphylaxis) after an insect sting, resulting in airway obstruction and a drop in blood pressure. Which action should the nurse prioritize first? 

A. Documenting the specific trigger in the patient's health history 

B. Educating the patient on the future use of an EpiPen 

C. Supporting the airway, breathing, and circulation (ABCs)

D. Administering a non-specific blood test for CRP


C: In an anaphylactic reaction, the nurse's immediate responsibility is the support of the patient's ABCs (airway, breathing, and circulation). 

600

A patient with an uncontrolled systemic infection is showing signs of Septic Shock and Multiorgan Dysfunction Syndrome (MODS). Which clinical finding should the nurse interpret as a sign of progressing vascular and renal failure? 

A. Increased blood pressure and increased urine output 

B. Hypotension and decreased urine output (oliguria) 

C. Localized redness and swelling at the wound site 

D. Seizures and mental status changes

B: In uncontrolled infection, increased vascular permeability causes fluid to shift out of vessels, leading to hypotension and reduced blood flow to the kidneys, resulting in oliguria. 

600

A nurse is developing a plan of care for an older adult patient with poor peripheral perfusion, protein-calorie malnutrition, and limited mobility. Which combination of interventions is most critical for the nurse to implement to prevent impaired tissue integrity? 

A. Encourage high-carbohydrate snacks and use a scented lotion for dryness. 

B. Frequent repositioning, ensuring adequate protein/Vitamin C intake, and moisture management. 

C. Daily soap baths to maintain hygiene and placing the patient in a chair for 4 hours daily. 

D. Limiting fluid intake to prevent edema and using a mechanical debridement tool daily.

B: Effective prevention involves a multi-faceted approach: pressure relief (repositioning), nutrition (protein and vitamins A and C are vital for collagen synthesis), and moisture management to keep skin healthy. 

600

A patient is currently experiencing an acute "Alarm Response" to a traumatic event, exhibiting high anxiety, dilated pupils, and a rapid pulse. Which nursing intervention is the priority when communicating with this patient? 

A. Provide a detailed, complex explanation of the General Adaptation Syndrome. 

B. Encourage the patient to immediately begin meaning-focused journaling. 

C. Use a gentle, reassuring tone and provide short, clear instructions. 

D. Leave the patient in a brightly lit, busy area to keep them alert.


B: When a patient is in the alarm stage, the nurse should remain calm, use a reassuring tone, and offer short instructions to help the patient feel safe and regain control. 

600

Which patient should the nurse identify as being at the highest risk for developing a mood spectrum disorder based on the presence of multiple risk factors? 

A. A healthy school-age child with strong peer relationships. 

B. An adolescent with a family history of mental illness who is experiencing significant trauma. 

C. An older adult who uses life experience and healthy coping strategies to manage stress. 

D. A middle-aged adult attending a stress management seminar for primary prevention.

B: Populations at higher risk for mood spectrum disorders include those with a family history of mental illness, individuals experiencing trauma, and adolescents due to developmental and hormonal changes. 

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