Topic 12:Intracellular Compartments and Protein Sorting I
A temporary and dynamic group that can be formed of nucleic acids and proteins
What is a biomolecular condensate?
Translocator used for insertion and folding of B-barrel proteins in the outer mitochondrial membrane.
What are SAM complexes?
Types of Vesicles in cells
What is Clathrin, COP1, COP2, and retromer
The four mechanisms used for protein movement between compartments.
What is protein translocation, gated transport, vesicular transport, and engulfment?
Protein translocators of the inner Mitochondria membrane
What are TIM22, TIM23, and OXA complexes
These proteins assist in membrane bending during vesicle formation due to their positive charge
What are Bar proteins?
Synthesizes cholesterol and modifies it to make hormones
What is Smooth Endoplasmic Reticulum
This chromatin-associated protein encourages GTP exchange for its associated protein in the nucleus
What is Ran-GEF?
Transmembrane receptor proteins found in the trans Golgi network (TGN) that help package lysosomal hydrolases into clathrin-coated vesicles.
What are M6P receptor proteins?
This particle binds to proteins destined for the endoplasmic reticulum and brings it to the ER membrane
What is SRP?
Found in all human cells, this phospholipid class is particularly abundant in the brain, as it is a major constituent of myelin.
What are plasmalogens?
A type of transport vesicle that is caged in proteins that are shed before fusing with their destination.
What is a coated vesicle?
These signal sequences are found on proteins to allow their transport into the nucleus from the cytosol, and are typically enriched in positively-charged amino acids.
What are nuclear localization signals (NLSs)?
A ceramide is a precursor to two types of lipids. List the two lipids.
What are glycosphingolipids and sphingomyelin?
Four regulated exocytosis processes that lead to plasma membrane enlargement.
What is cytokinesis, phagocytosis, plasma membrane repair, and cellularization?