Medical Uses
Mechanism of action
Use & Safety
Adverse Effects
100

Morphine is most commonly used to manage this type of pain.

What is severe or chronic pain?

100

Morphine binds primarily to these receptors in the brain and spinal cord.

What are opioid receptors?

100

This medication can reverse a morphine overdose.

What is naloxone (Narcan)?

100

The most common side effect of morphine that affects the bowels.

What is constipation?

200

Morphine is classified as this type of drug, acting on opioid receptors.

What is an opioid analgesic?

200

Morphine reduces pain by decreasing the release of this neurotransmitter.

What is substance P?

200

Patients should never combine morphine with this class of drugs due to risk of respiratory failure.

What are benzodiazepines or sedatives?

200

Morphine can cause constricted pupils, a sign known as this.

What is miosis?

300

In hospitals, morphine is often given by this route for rapid pain control.

What is intravenous (IV) administration?

300

This brain system, involved in reward and pleasure, is also affected by morphine.

What is the mesolimbic dopamine system?

300

Morphine should never be crushed or chewed if it’s in this type of formulation.

What is an extended-release tablet or capsule?

300

This type of pain relief tolerance may develop over time, requiring higher doses.

What is opioid tolerance?

400

Morphine can also be used to relieve this symptom in patients with advanced heart failure.

What is shortness of breath (dyspnea)?

400

Morphine’s effects on the brainstem can cause this dangerous side effect at high doses.

What is respiratory depression?

400

Before giving morphine, always check this vital sign to ensure patient safety.

What is respiratory rate?

400

The classic triad of morphine overdose includes coma, respiratory depression, and this.

What are pinpoint pupils?

500

This synthetic opioid is often compared to morphine but is many times stronger.

What is fentanyl?

500

Morphine’s ability to cross this barrier allows it to reach the brain.  

What is the blood–brain barrier?

500

Morphine should only be used under this kind of supervision.

What is medical supervision?

500

If morphine causes nausea, patients may be advised to take it with this.

What is food or a light snack?

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