History
20th-century physician developed the APGAR score
Dr Virginia Apgar
Valvular lesion classically associated with a “mid-diastolic rumble” at the apex
mitral stenosis
antibiotic is associated with risk of aortic aneurysm and dissection
Fluoroquinolones
antidote for acetaminophen overdose.
N-acetylcysteine
most common cause of septic shock in the ICU.
Gram Negative Bacteremias
Persian polymath wrote “The Canon of Medicine,” a standard text for centuries
Avicenna (Ibn Sina)
This ECG finding is pathognomonic for pericarditis (2 parts)
diffuse ST-segment elevation with PR depression
parasite causes Chagas disease and what is the classic cardiac manifestation? (2parts)
Trypanosoma Cruzi and dilated CMP w/ apical aneurysm
class of antihypertensive drugs can precipitate gout flares
thiazide diuretics
criteria used to assess severity of acute pancreatitis at admission
Ransons
discovery of penicillin in 1928 is credited to this scientist
Alexander Fleming
The diagnostic criteria for Takotsubo cardiomyopathy include absence of this condition.
Obstructive coronary artery disease
triad of fever, back pain, and neurologic deficits raises concern for this condition.
spinal epidural abscess
CYP2C19 polymorphism most significantly impacts metabolism of this commonly used antiplatelet agent
clopidogrel
what is the key difference in indication between VA-ECMO and VV-ECMO?
VA provides both cardiac and respiratory support, while VV provides only respiratory support
developed the first effective vaccine, and for what disease? (2 part)
Edward Jenner - Small Pox
The primary mechanism of action of sacubitril in heart failure therapy.
neprilysin inhibition
treatment of choice for cryptococcal meningitis in HIV patients (2 parts)
amphotericin B + flucytosine
most nephrotoxic calcineurin inhibitor
cyclosporine
classic triad of fat embolism syndrome
Respiratory distress, neurological abnormalities, petechial rash
German physician won the Nobel Prize for discovering the tubercle bacillus in 1882?
Robert Koch
genetic mutation is most commonly implicated in familial hypertrophic cardiomyopathy
mutation in the β-myosin heavy chain gene (MYH7)
mechanism behind daptomycin inactivation in the lungs
binds pulmonary surfactant, rendering it ineffective
Unique toxicity of cefepime in renal failure
Neurotoxicity (encephalopathy, seizures)
Formula for driving pressures
PPlat - PEEP