Proteins
Complementary messenger - RNA?
CAA GGT
GUU CCA
What is a missense point mutation?
When a single base in the DNA is substituted changing the amino acid.
How many nucleotide codes for each amino acid?
3
What type of protein is sickle cell disease?
Hemoglobin.
Whats the location of the mutation on the HbA sequence?
The mutation happens on the sixth codon.
what is the significance of the start codon AUG?
It signals the beginning of protein synthesis.
How does the HbS protein function differently than the HbA protein in red blood cells?
The HbS protein functions differently by making hemoglobin stick together and bending RBC's into sickle shapes.
Which amino acid gets changed in the HbA sequence?
Glutamic acid turns into valine, changing hemoglobin’s shape and causing cells to sickle.
In the sequence, GAG, what does the codon change to, what does this show?
GAG turns to GTG (A to T); it shows how a singular codon change can completely change a protein's function.