Looks like Swiss cheese
These function to reabsorb bone
What are osteoclasts?
Slide 18
This non-invasive test estimates skeletal mass and is the standard for measuring bone mineral density
What is a DEXA scan?
Slide 29
This doctor's colleagues call them Dr. Hot
Who is Dr. George?
Calcitriol binds to this receptor
What is the vitamin D receptor (VDR)?
Slide 8
Side effects of this intranasally administered medication include nasal irritation and nose bleeds
What is calcitonin?
Slide 9
This is the most common cause of medication-induced osteoporosis
What are glucocorticoids?
Slide 27
This score represents a patient's bone density compared to a person of the same age
What is a Z-score?
Slide 31
This professor is currently getting their master's in health education from Johns Hopkins. They also recently went to a concert in Baltimore to see the Swedish rock band, Ghost.
Who is Dr. Small?
This class of drugs are incorporated in bone, where they remain unmetabolized
What are bisphosphonates?
Slide 11
Denosumab is well tolerated, however it may cause these 2 side effects
What are dermatitis and rashes?
Slide 12
Fractures here are the most common early skeletal consequence of estrogen deficiency
What are the vertebrae?
Slide 25
This is the T-score associated with osteopenia
What is -1.0 to -2.5?
Slide 6
This professor makes ganache balls to use as gifts every year for Christmas
Who is Dr. Shipley?
What is the Parathyroid hormone (PTH) receptor?
Slide 16
A rare but serious side effect of this medication class is osteonecrosis of the jaw
What are bisphosphonates?
Increased risk of ONJ with long-term BP therapy (> 3 years), after tooth extractions and in cancer patients receiving high-dose IV BP therapy
Slide 11
Serum vitamin D should be greater than this for optimal skeletal health
What is 30 ng/mL?
Calcium per day: 1000-1200 mg
Slide 23
The WHO recommends using the lowest T-score between these 3 locations to diagnose osteoporosis
What are the lumbar spine (L1-L4), femoral neck, or total proximal femur?
Slide 33
This professor lived in Germany and France and played lacrosse in HS and college
Who is Dr. V?
This osteoporosis medication is a human monoclonal antibody that binds to RANKL
What is Denosumab?
Slide 12
Along with abaloparatide, this drug contains a boxed warning against the use in patients with increased baseline risk of osteosarcoma
What is Teriparatide?
Slide 17
Smoking has these two effects that contribute to the pathophysiology of osteoporosis
What are modify estrogen metabolism and produce toxic effects on osteoblasts?
Slide 28
These two populations get bone mineral density screening regardless of risk factors
What are women aged ≥65 and men aged ≥70?
Slide 34
This professor helps teach self defense classes
Who is Dr. Pettitt?
Romosozumab binds to this
What is sclerostin?
Slide 19
This drug for osteoporosis should not be used in patients who have had a heart attack or stroke within the previous year
What is Romosozumab?
Slide 20