Myeloma
The primary disease site where multiple myeloma originates
Bone marrow
This bone tumor is the most common primary bone cancer in children and adolescents
Osteosarcoma
A symptom of bone tumors you can see or feel
Palpable mass / soft tissue swelling / lump
Primary bone tumors are generally considered this in terms of radiation sensitivity
Radioresistant
The typical mechanism of spread for multiple myeloma and primary bone tumors
Hematogenous / bloodstream
The median age at diagnosis for multiple myeloma
69-70 years
This bone tumor originates from cartilage cells
Chondrosarcoma
The most common symptom of multiple myeloma
Bone pain
Although uncommon, this RT technique may be used in preparation for stem cell transplants in myeloma cases
Total body irradiation (TBI)
Without this type of treatment, most osteosarcoma patients will develop distant metastases
Chemotherapy
MGUS (monoclonal gammopathy of unknown significance)
The most common site of metastasis for primary bone tumors
Lungs
Bone tumors can weaken the bone and lead to this type of fracture
Pathologic fracture
The most common treatment site for myeloma RT
Spine
Unlike multiple myeloma, this plasma cell tumor occurs as a single lesion
Plasmacytoma
This imaging study is used for detecting lytic lesions throughout the entire body
Skeletal survey
The three most common locations of osteosarcoma
Distal femur, proximal tibia, proximal humerus
The four myeloma-defining end-organ damage symptoms
CRAB: Calcium elevation, Renal impairment, Anemia, Bone lesions