Motor Units
Sliding Filament 1
(Theory)
Muscle Anatomy
Contraction Cycle
Sarcomere
100

What is a "Motor Unit"

One motor neuron plus all of the muscle fibers that it stimulates. 

100
Which is the thick filament?
Myosin
100

Many muscle fibers make up a...

Fascicle

100
What causes myosin to detach from actin?
ATP binding to myosin head
100
What is the name of the protein that blocks myosin binding sites on actin?

Tropomyosin

200

What type of neurotransmitter is released to stimulate muscle contraction?

Acetylcholine (ACh)

200

Which is the thin filament?

Actin
200

Many fascicles make up a...

Muscle

200

What is a "cross bridge"

When myosin heads bind to actin filaments. 

200

What is the function of calcium binding to troponin?

Alters shape of troponin and moves tropomyosin off myosin binding site on actin

300

What does calcium bind to in the muscle cell?

Troponin

300

What is blocking myosin from binding to actin when a muscle is relaxed?

Tropomyosin

300

Many myofibrils make up a...

Muscle fiber
300

What is the event called when myosin crossbridges pull actin towards the center of the sarcomere?

Power stroke

300
When a muscle contracts, each end of the sarcomere is pulled towards the middle of the sarcomere. What is this middle line called?
The M Line
400

What happens when when acetylcholine is released?

It stimulates the release of calcium from the sarcoplasmic reticulum. 

400

Which filament moves during a contraction?

Actin

400

What structure releases calcium?

Sarcoplasmic Reticulum

400

What controls the movement of tropomyosin?

Troponin, regulated by calcium. 

400

What part of the sarcomere contains ONLY actin?

I band

500
What types of movements are stimulated by large motor units? What about small motor units?

Large motor units -> powerful, non-specific movements

Small motor units -> small, specific movements

500
Walk me through the step by step process of muscle contraction from nervous stimulation to the power stroke. 

Motor neuron releases acetylcholine -> acetylcholine causes the release of calcium from the sarcoplasmic reticulum -> calcium binds to troponin -> troponin moves tropomyosin off of the myosin binding sites -> myosin binds to actin -> muscle contracts

500

What surrounds the muscle as a whole?

Epimysium

500

What is the last step of the cross bridge cycle?

ATP binds to the myosin head causing the myosin to release from the actin and reset for another power stroke.

500

Which areas of the sarcomere essentially disappear when a muscle contracts?

The I band and the H zone. 

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