Who is that Myeloma KOL?
This KOL who was an early adopter of Daratumumab, recently moved from North Carolina to New York City.
Who is Saad Usmani ?
With the pivotal studies named for constellations, this drug was the first monoclonal antibody approved for myeloma.
This staging system predated the ISS
What is the Salmon-Durie Staging System?
The highest response category according to conventional criteria, the patient must have clearance of the paraprotein in the blood and urine, as well as any plasmacytomas, and a bone marrow plasma cell percentage <5%. In addition, normalization of serum FLC and negative plasma cells by 2-4 color flow is required.
What is Stringent Complete Response (sCR)?
This SLT member recently retired in December 2023 and went into Biotech.
Who is Peter Lebowitz ?
This KOL has a practice in Beverly Hills and holds the distinction as being half of this historic staging system.
Who is Brian Durie?
This series of studies with an peaceful name investigated an antibody drug conjugate for myeloma.
What are the DreaMM studies?
These response criteria predated the IWMG consensus guidelines.
What are the EBMT guidelines?
This response criteria is only valid for Relapsed Refractory Myeloma studies and not in the newly diagnosed setting.
What is Minimal Response (MR)?
This SLT member recently announced her departure after leading the Data Sciences Group at JnJ for several years.
Who is Najat Khan?
This KOL based in the Netherlands is the current president of the European Myeloma Network
Who is Pieter Sonneveld ?
This series of studies investigated an oral proteasome inhibitor in myeloma.
What are the TourMMaline studies?
Considered one of the "Grandfathers of Myeloma," this KOL is still in practice at Mayo clinic and recently published an autobiography
Who is Bob Kyle ?
This response category requires clearance of the monoclonal protein in the blood and urine regardless of whether the myeloma protein was present at baseline in the blood, urine, both or neither.
What is Complete Response (CR)?
This former NJCI director was the Pharmaceutical Head for several years before joining the Innovation Center.
Who is Bill Hait?
This KOL from Germany is the leader of the GMMG study group
Who is Hartmut Goldschmidt ?
This study gave clarity to the question on whether KMP or VMP was better in the front line Myeloma setting.
What is the CLARION study?
This physician was credited for first describing the excess protein in the urine of myeloma patients in the mid-1800s.
Who is Dr. Henry Bence-Jones?
This response category is concluded if there is no objective response in a newly diagnosed patient after post-baseline disease assessments are obtained
What is Stable Disease (SD)?
This former SLT member left to lead a company named after this remote island group off the coast of Ecuador
Who is Paul Stoffels ?
This KOL in Spain recently won the 2023 Bob Kyle Lifetime Achievement award from the IMS.
Who is Maravi Mateos ?
While seldom used in myeloma, this study helped establish this HDAC study as having activity in myeloma.
What is the PANORAMA study?
This physician published the first case of Multiple Myeloma in 1844 detailing the case of a 39yo woman named Sarah Newbury.
Who is Dr. Samuel Solly ?
This response category is no longer used by IWMG, but was concluded if the SPEP and UPEP dropped to zero, but there was still a residual positive IFE.
What is Near CR (nCR)?
This tall Belgian was the former Protocol Review Committee Chair and is currently the head of Heme Malignancies at Sanofi.
Who is Helgi Van De Velde?