Muscle Contraction
Myopathies General
Ryanodine Receptor 1 Related Myopathies
Myasthenia Gravis
100

Nictonic Acetylcholine Receptor

What receptors are found at the neuromuscular junction?

100

Inherited and Acquired

What are the two groups of myopathies?

100

Genetic mutations in RyR1 coding gene

What causes dysfunction of the ryanodine receptor 1 resulting in myopathies?

100

an autoimmune disease in which antibodies bind to the acetylcholine receptors in the postsynaptic membrane at the neuromuscular junction (NMJ)

What is Myasthenia gravis?

200

Epimysium, Perimysium, Endomysium

What are the layers of connective tissue surrounding skeletal muscle?

200

A disease of muscles

What is myopathy?

200

Physical therapy, specialized braces, and surgical intervention

What are treatments (not cures) for CCD?

200

Condition caused by weakness of eye muscles resulting in double vision

What is diplopia?

300

Undergoes a conformational change upon detection of an action potential

What is the dihydropyridine receptor?

300

Burning and tickling feeling in the extremities (especially arms, legs, hands, and feet)

What is Paresthesias?

300

Weakness in proximal muscles

A symptom of Central Core Disease (CCD) is what?

300

drooping of the eyelids

 What is ptosis?

400

The electrical stimulus that leads to muscle contraction

What is an action potential?

400

Toxic Myopathies, Inflammatory Myopathies, and Myopathies associated with Systemic Conditions

What are the categories of acquired myopathy?

400

Ryanodine Receptor 2 (RyR2)

What is the ryanodine receptor isoform present on cardiac muscle?

400

Transmembrane protein needed to stimulate the signalling pathway resulting in clustering of Acetylcholine receptors on the postsynaptic membrane

What is muscle-specific kinase protein (MuSK)?

500

Periosteum

What is the connective tissue wrapped around the bone?


500

A general symptom that is seen in inherited myopathies.

What is dark-coloured urine?

500

Scoliosis

What is an abnormal curvature of the spine?

500

Condition in which loss of the presynaptic voltage-gated calcium channels results in reduced release of the acetylcholine transmitter

What is Lambert-Eaton myasthenic syndrome?

M
e
n
u