Pass the Class
Side Effects May Include...
Combination Tablets
How Stuff Works
Potpourri
100
3TC
What is an NRTI?
100
Orthostatic hypotension
What is maraviroc?
100
The combination tablet used to treat HIV and HBV
What is Truvada?
100
Following phosphorylation, these nucleotide analogs are incorporated into viral DNA to prevent further elongation
What is an NRTI?
100
The only antiretroviral given subcutaneously
What is enfuvirtide?
200
DTG
What is an INSTI?
200
Metabolic abnormalities
What are PIs?
200
The NRTI backbone for which anemia is a possible AE.
What is Combivir?
200
Prevent cleaving of polyprotein chains and maturation of virus
What are protease inhibitors?
200
The two cytosine analogs that should never be given together.
What are lamivudine and emtricitabine?
300
Mitochondrial toxicity is the class adverse effect.
What are the NRTIs?
300
Feeling "hungover"
What is efavirenz?
300
The components of the first single tablet regimen known to cause CNS effects.
What are tenofovir, emtricitabine, efavirenz?
300
NNRTIs
What is bind to reverse transcriptase, leading to a conformational change to prevent activity?
300
The antiretroviral with a sulfa moiety
What is darunavir?
400
The abbreviations for the PIs coformulated with cobicistat
What are ATV and DRV?
400
CK elevations
What is raltegravir?
400
The components of the 2 NRTI tablet that requires HLA B*5701 testing prior to prescribing.
What are abacavir and lamivudine?
400
Integrase inhibitors
What is inhibition of incorporation of viral DNA into host DNA by integrase through binding of magnesium or manganese cofactors of integrase?
400
600mg po BID is the dose
What is the dose of maraviroc when given with a strong 3A4 inducer?
500
The receptor MVC antagonizes
What is CCR5?
500
Increased bilirubin
What is atazanavir?
500
The components of the single tablet regimen known to have significant CYP interactions.
What are tenofovir, emtricitabine, elvitegravir, and cobicistat?
500
Mechanism of maraviroc
What is binds to CCR5 to inhibit HIV binding to host CD4 cells, eliminating attachment and entry?
500
Two pharmacokinetic boosters
What are ritonavir and cobicistat?
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