Seizures and withdrawal symptoms that last as long as 4-6 months occur as a result of _____ exposure during pregnancy.
Heroin and opiates
This α-2 agonist is often added as an adjunct for severe withdrawal.
What is Clonidine
A major criticism of Finnegan scoring is that individual items rely heavily on this type of assessment, making scores variable between nurses.
What is subjective scoring?
Significantly reduced fetal growth, low birth weight and prolonged learning disabilities occur as a result of this exposure
What is low-stimulation care (dim lights, reduced noise, clustered care)?
A diagnosis of NOWS/NAS meets criteria for immediate qualification to infants and toddlers.
What is fact?
Deformities of the head and face, heart defects, and intellectual disabilities occur as a result of ____ use during pregnancy.
What is alcohol?
Phenobarbital has been the preferred second-line therapy for NAS treatment but has lost favor due to this concern noted in animal studies.
What is neurotoxicity and adverse developmental outcomes?
Several neonatal abstinence scoring systems are available for observation of affected infants and for determination of the need for pharmacologic treatment. Of the following, the most comprehensive, widely used, and adapted neonatal abstinence scoring system is the:
What is the Finnegan Scoring system?
A landmark 2023 NEJM cluster-randomized trial found that this assessment method significantly reduced pharmacologic treatment and LOS without increasing adverse events.
What is the Eat-Sleep-Console (ESC) model?
Prescription amphetamines do not increase the neonatal risk of NAS.
What is myth?
A neonate in the nursery is showing subtle signs of withdrawal, warranting NICU consultation. Mom's history is significant for anxiety and asthma with a negative UDS. What is most likely causing the symptoms?
What is SSRI exposure?
What is 5-7 days?
Under the Finnegan scoring system, an infant must score __ or ___ to qualify for pharmacological therapy.
What is three scores ≥ 8 or this number of scores ≥ 12?
All infants with chronic opoid exposure should be observed for at least what amount of time.
What is 72 hours?
Naloxone should be considered in the DR or early neonatal period in neonates with respiratory failure thought to be due to maternal substance abuse.
What is myth?
Maternal use of this drug is most correlated with Sudden Infant Death Syndrome (SIDS)
Compared with morphine, methadone has what advantage in treating neonates with NAS
What is less frequent dosing?
The MOTHER study compared methadone vs. buprenorphine and relied primarily on this scoring system to assess withdrawal severity.
What is the modified Finnegan score?
The main criterion for starting medication under ESC is failure of these to support the infant.
What are functional assessments (eat, sleep, console)?
Universal urine drug screening is the gold standard for screening neonates for drug exposure
What is myth?
Significantly reduced fetal growth, low birth weight and prolonged learning disabilities occur as a result of this exposure
What is Cocaine?
This opioid medication, given sublingually, is gaining popularity for faster weaning and shorter LOS.
What is Buprenorphine?
This NAS/NOWS scoring system is considered the gold standard per the AAP 2020 NOWS report.
What is none?
The minimum “sleep duration” considered adequate in ESC.
What is "one hour"?
Mothers with a history of maternal drug use under a MAT (maternal assistance program) do not have a contraindication to breastfeeding.
What is myth?