Guillian-Barré + Multiple Sclerosis
What are both GB and MS attacking?
The myelin sheaths of muscle fibers
What cells are attacking the neurotransmitters in this autoimmune disease?
T and B cells
Parkinson's is a lack of ______, and increase in_____?
dopamine, acetycholine
what are causes of ALS?
genetic, family history, repeated head blows
What is the most common symptom of epilepsy?
seizures
What are symptoms of multiple sclerosis, and what key one makes it different from GB?
muscle flaccidity/ weakness, pain with movement; OPTIC fibers attacked, loss of sight
How does an individuals energy go throughout the day? higher--> lower? same throughout the day?
high in morning, low in afternoon
what age group is most commonly affected by parkinson's?
elderly (50 +)
Voluntary muscle, cognitive loss
what are the stages of migraine?
prodrome
aura
pain
postdrome
GB occurs after _____, and moves _____. After ___, you are considered to have reached full extent of recovery
infection, ascending/up, 2
How does MG progress
descending disease
what are some of the ANS symptoms?
orthostastic hypotension, gastrointestinal (constipation), and sleep issues (insomnia, restless leg)
Where in the muscles does ALS attack?
the motor neurons
what are the two types of seizure, and what makes them different?
generalized +focal; focal is loacalized to one hemisphere, generalized starts in one and spreads
Which cells are responsible for attacking the myelin, and what part of the nervous system specifically do they attack?
overly sensitive T Cells, attack the CNS
How do the two forms differ from eachother?
ocular is just localized to the eyelids and extraocular muscles, while generalized attacks muscles throughout the limbs, esophagus, and respiratory muscles
how do we diagnose a patient with parkinson's?
physical presentation; there are no lab tests that can diagnose a patient
what is the end result of ALS, and why?
respiratory failure due to diaphragm dysfunction
how do we differentiate between tension headaches and migraines?
tensions headaches do not get worse w/ movement
What makes diagnosis of MS difficult?
The disease needs to be more advanced, in order to see demyelination on diagnostic imaging
what is the biggest emergency associated with MG, and what is critical about it?
myasthenia crisis; medical emergency, ANS crash- extreme respiratory distress to the point of being unable to breathe
What does TRAP stand for?
tremor, rigidity, achnesia (bradykinesia), postural slope
what are the two types of ALS?
familial and sporadic
How is an angiogram utilized for headaches?
shows vessel contrast for dissection, tears, aneurysms