Meningitis and Encephalopathy
Myasthenia Gravis and Cholinergic Pharmacy
Parkinson's Disease and Dopaminergics
Multiple Sclerosis and Immunodulators
Seizure Disorders & Antiepileptics
Stroke & Thrombolytics
IICP & Altered level of conciseness
100

This clinical sign is present when the patient's hips and knees involuntarily flex in response to the nurse flexing the patient's neck forward

Brudzinski's Sign

100

This "test" involves administering IV edrophonium; a temporary improvement in muscle strength indicates a positive diagnosis for myasthenia gravis

Tensilon Test 

100

The nurse should educate the patient taking Carpidopa/ Levodopa to avoid high amounts of this macronutrient during the day to prevent decreased absorption of the drug

Protein 

100

A patient with MS suddenly develops significantly worsening neurologic symptoms. The nurse should recognize this as potentially representing this

MS relapse/exacerbation

100

This medication is the first-line "drug of choice" for terminating Status Epilepticus due to its rapid ability to enhance GABA activity

Valium (Diazepam) drug of choice

contraindicated in narrow angle glaucoma 

antidote: IV flumazenil

Administer slowly to prevent respiratory depression

100

This diagnostic test must be completed within 30 minutes of a suspected stroke patient's arrival to rule out a hemorrhagic stroke

CT scan! 

100

This is the earliest and most sensitive indicator that a patient’s neurological status is deteriorating

change in Level of Consciousness (LOC)

200

After starting appropriate antibiotic therapy for bacterial meningitis, the nurse must maintain droplet precautions for this specific length of time

24 hours 

200

To maximize drug efficacy and minimize the risk of aspiration during meals, the nurse should administer Pyridostigmine how long before allowing the client to eat 

30-60 minutes 

Initial choice for increasing muscle strength in MG 

Medium acting

Antidote: Atropine Sulfate 

Adverse Effects: cardiac dysrhythmias, COPD, HTN, bradycardia, seizures 


200

Originally developed as an antiviral for influenza, this medication is used for Parkinson's to relieve symptoms for a limited amount of time 

Amantadine HCL 

side effects increase with other Parkinson's drugs. 

Don't give to RENAL failure or dialysis

Increase oral hygiene, avoid alcohol caffeine and smoking, avoid heat extremes, glaucoma

200

This immunomodulator is considered a first-line treatment for MS

interferon beta-1a/b

as well as corticosteroids, anti-inflammatories, and muscle relaxants 

200

Side effect of gingival hyperplasia, liver toxicity, agranulocytosis, hirsutism, SJS, and suicidal ideation are common from what medication?

Phenytoin (Hydrantoins) 

thin therapeutic window (10-20 mcg/mL)

avoid anticoagulants, backup birth control, take with milk or food 

200

A patient with damage to this side of the brain is likely to experience aphasia, impaired speech, and a slow, cautious behavioral style

Left side damage 

200

This group of late-stage IICP symptoms includes widening pulse pressure (increased systolic BP), bradycardia, and irregular respirations

Cushing's Triad- (opposite symptoms as stroke)

300

Before a patient undergoes this diagnostic procedure to analyze CSF, the nurse must ensure a CT scan is performed first if increased intracranial pressure (IICP) is suspected 

Lumbar puncture (spinal tap) 

You may see orders for corticosteroids and broad spectrum antibiotics ordered to help reduce inflammation 

300

If a patient experiences a cholingergic crisis (overdose) characterized by bradycardia and respiratory distress, the nurse should be prepared to administer this IV antidote 

IV atropine sulfate 

300

A nurse assessing a Parkinson's patient might observe this classic "pill-rolling" motion of the thumb and fingers 

resting tremor 

300

Patients starting interferon beta 1a/b should be prepared to feel what sort of side effects

Flu like symptoms 

also be aware of adverse effects- teratogenic effects- avoid pregnancy, and myelosupression (risk for infection) and hepatotoxicity 

300

For a patient taking Phenytoin, the nurse must monitor labs to ensure the medication stays within this therapeutic window.

10-20 mcg/mL. Anything over 30mcg/mL is TOXIC 

300

While rt-PA can often be given up to 4.5 hours after the "last known normal," this age group is excluded if the window exceeds 3 hours

over the age of 80

300

This type of abnormal posturing, characterized by internal rotation and adduction of the arms, indicates damage to the corticospinal tract

Decorticate posturing

400

While meningitis is an inflammation of the membranes, this condition is an acute inflammation of the brain tissue itself, often caused by Herpes Simplex Virus

Encephalitis 

Priority is to find out what started it** treat with antivirals and monitor labs 

another manifestation is phonophobia and nuchal rigidity (neck can't bend forward) 

400

This priority nursing assessment for a MG patient is essential because the disease could can lead to weakened diaphragm and intercostal muscles 

Respiratory Status- difficulty breathing 

400

The use of anticholinergic medications like Atropine to treat PD tremors is strictly contraindicated in patients with this specific eye condition

Narrow-angle glaucoma 

400

The nurse should instruct the MS patient to avoid these triggers, which are known to cause exacerbations of the disease 

temperature extremes (Heat and cold), stress, and infection 

400

During a tonic-clonic seizure, the nurse should never attempt to do this to the patient's jaw or mouth

force the mouth open or ever stick anything in it 

400

Before administering thrombolytics, the nurse must ensure the patient's blood pressure is below this specific systolic threshold

Systolic BP greater than 185

or Diastolic BP greater than 110 

make sure to know exclusion criteria**

400

A nurse observing "extensor posturing" knows this indicates a more severe injury involving this specific part of the brain

Brain Stem 

500

This assessment finding, characterized by pain or resistance when the nurse attempts to straighten the patient's leg while the hip is flexed at 90 degrees is a classic sign of meningeal irritation

Kernig's Sign 

500

Too little acetylcholinesterase inhibitor medication can result in this type of crisis

Myasthenic Crisis

500

This term describes "mask-like" blank expression and slow, shuffling gait characteristic of advanced Parkinson's disease 

Bradykinesia 

500

This specific clinical manifestation of MS involves a sensation of an electric shock that travels down the spine when the patient moves their head. 

Lhermitt's sign- (electric shock sensations)

500

This term refers to the period of confusion, fatigue, and headache that follows a generalized seizure

postictal state

500

If a patient receiving rt-PA begins to bleed uncontrollably, the nurse should have this specific hemostatic antidote ready for administration

Aminocaproic acid- stops bleeding 

500

To promote venous drainage and help lower intracranial pressure, the nurse should do these early interventions

Elevate HOB, keep neck in neutral position, no neck or hip flexion 

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