Vascular Territories
Brainstem Localization
Cortical Functions
Stroke Syndromes
Imaging and Anatomy Pearls
100

This artery commonly causes contralateral face and arm weakness when occluded.

A. Anterior cerebral artery
B. Posterior cerebral artery
C. Middle cerebral artery
D. Basilar artery

Middle Cerebral Artery

100

Ipsilateral facial paralysis with contralateral hemiparesis localizes the lesion to the:

A. Medulla
B. Midbrain
C. Pons
D. Cerebellum

Pons

100

Finger agnosia, acalculia, and left‑right confusion point to damage in the:

A. Right frontal lobe
B. Dominant parietal lobe
C. Non‑dominant temporal lobe
D. Occipital cortex

Dominant Parietal Lobe

100

Pure motor hemiparesis without cortical signs most often results from infarction of the:

A. Thalamus
B. Internal capsule
C. Caudate nucleus
D. Primary motor cortex

Internal Capsule

100

Early MCA stroke often causes loss of gray‑white differentiation in the:

A. Caudate nucleus
B. Insular cortex
C. Occipital lobe
D. Thalamus

Insular Cortex

200

Infarcts in this vascular territory often cause contralateral leg weakness and behavioral changes.

A. Middle Cerebral Artery
B. Posterior Cerebral Artery
C. Anterior Cerebral Artery
D. Vertebral artery

Anterior Cerebral Artery

200

Hoarseness, dysphagia, ipsilateral facial pain loss, and contralateral body pain loss indicate:

A. Medial medullary syndrome
B. Lateral medullary (Wallenberg) syndrome
C. Weber syndrome
D. Claude syndrome

Wallenberg Syndrome

200

Non‑fluent, effortful speech with intact comprehension localizes to:

A. Wernicke’s area
B. Arcuate fasciculus
C. Broca’s area
D. Insular cortex

Broca's Area

200

A pure sensory stroke most commonly involves the:

A. Post‑central gyrus
B. Cerebellum
C. Thalamus
D. Brainstem tegmentum

Thalamus

200

Early middle cerebral artery (MCA) infarcts may spare which region due to more robust collateral blood supply?

A. Primary motor cortex
B. Primary visual cortex
C. Internal capsule
D. Insular cortex

Primary Visual Cortex
300

Severe deficits including coma and “crossed” brainstem findings suggest occlusion of which artery?

A. Posterior inferior cerebellar artery
B. Basilar artery
C. Anterior spinal artery
D. Posterior cerebral artery

Basilar Artery

300

Loss of pain and temperature sensation on the ipsilateral face implicates damage to the:

A. Ventral trigeminothalamic tract
B. Main sensory trigeminal nucleus
C. Spinal trigeminal nucleus and tract
D. Medial lemniscus

Spinal Trigeminal Nucleus and Tract

300

A right hemispheric stroke most commonly causes:

A. Expressive aphasia
B. Gerstmann syndrome
C. Hemispatial neglect
D. Alexia without agraphia

Hemispatial Neglect

300

Ataxic hemiparesis is most often due to infarction in the:

A. Medulla
B. Internal capsule or pons
C. Occipital lobe
D. Cerebellar hemisphere

Internal Capsule or Pons

300

This brain region is most vulnerable to global hypoxia:

A. Putamen
B. Purkinje cells
C. CA1 hippocampal neurons
D. Posterior limb of internal capsule

CA1 Hippocampal Neurons

400

This artery supplies the occipital lobe and medial temporal lobe.

A. Middle cerebral artery
B. Anterior choroidal artery
C. Posterior cerebral artery
D. Superior cerebellar artery

Posterior Cerebral Artery

400

Locked‑in syndrome results from infarction of which structure?

A. Dorsal midbrain
B. Medial medulla
C. Ventral pons
D. Cerebellar vermis

Ventral Pons

400

Fluent but meaningless speech with impaired comprehension indicates damage to:

A. Inferior frontal gyrus
B. Posterior superior temporal gyrus
C. Supplementary motor area
D. Angular gyrus

Posterior Superior Temporal Gyrus

400

Weber syndrome localizes to the:

A. Pons
B. Medulla
C. Midbrain
D. Thalamus

Midbrain

400

An intracerebral hemorrhage classically causes gaze deviation toward the lesion when it involves which brain region?

A. Occipital lobe
B. Temporal lobe
C. Frontal lobe
D. Parietal lobe

Frontal Lobe

500

Alexia without agraphia most classically results from infarction in which vessel territory?

A. Left MCA
B. Right PCA
C. Left PCA
D. Left ACA

Left PCA

500

Ipsilateral tongue deviation with contralateral body weakness localizes the lesion to the:

A. Pons
B. Medial medulla
C. Lateral medulla
D. Midbrain

Medial Medulla

500

Inability to perform learned motor tasks despite intact strength is called:

A. Ataxia
B. Apraxia
C. Agnosia
D. Dysmetria

Apraxia

500

Decreased consciousness, vertical gaze palsy, and memory impairment suggest infarction of the:

A. Basal ganglia
B. Medial temporal lobe
C. Paramedian thalamus
D. Cerebellar vermis

Paramedian Thalamus

500

Watershed infarcts most often occur between which territories?

A. ACA–PCA
B. MCA–PCA
C. ACA–MCA
D. Basilar–PCA

ACA-MCA

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