Lingo
Don't
do that!
do that!
Name that disease
Don't be so sensitive
Myasthenia Gravis
100
What does ALS stand for?
Amyotrophic Lateral Sclerosis
100
When ordering PONV ppx for a patient with Parkinsons, this medication is best avoided
metoclopromaide + haloperidol (D2 receptor blockers)
100
This rare AD progressive neurodegenerative disease is associated with an increased trineucleotide repeat sequence on chromosome 4. (100 xtra points for naming the trineucleotide repeat sequence)
Huntington Disease (CAG)
100
The response to NDNMBs in a patient with MG?
Sensitive- try not to paralyze or if needed give BB doses
100
The characteristic pattern of weakness that occurs in patients with MG
improves w rest but deteriorates rapidly w exertion
200
This medical term refers to the delayed relaxation of skeletal muscle after voluntary contraction
myotonia
200
In a patient with this disease, you should avoid ordering potassium containing solutions
Hyperkalemic Periodic Paralysis
200
This disease is caused by loss of dopaminergic cells in basal ganglia
Parkinsons
200
Seen after giving a Huntington's patient succinylcholine
Prolonged paralysis
200
These types of antibodies are found 85-90% of pts with MG
IgG abs to postsynaptic ACh receptors at the NMJ
300
This large protein helps stabilize/support muscle membrane and its absence or sparsity leads to DMD and BMD respectively
Dystrophin
300
In patients with MS, this type of anesthesia has been associated with disease exacerbations.
Spinal Anesthesia
RA, epidural and GA are have not
300
This disease is the #1 risk factor for developing postoperative cognitive decline
Alzheimer's Disease
300
After giving a depolarizing NMB to a patient with muscular dystrophy, what may occur?
Hyperkalemia and rhabdhomyolysis
300
This is the preferred type of analgesia for laboring MG patients
Epidural (want to avoid NMBs + resp depression of GA)
400
This medical term refers to a sustained, involuntary muscle contractions
Dystonia
eg torticollis, blepharospasm
400
Avoid carboloading patients with this disease
Hypokalemic Periodic Paralysis
400
Charcot-Marie-Tooth Disease
400
Effect of NDNMBs on patients with CMT
sensitive --> prolonged effect
400
This test may help differentiate a cholinergic crisis from a myasthenic crisis. 100 xtra points for both names of this test
Edrophonium (tensilon) test
500
The portion of the brainstem that controls involuntary functions like breathing, swallowing, and speech. Composed of the medulla oblongata, pons, and cerebellum
Bulbar Region
500
In MS, Anesthetic goals include fluid homeostasis, normal hemodynamics and maintaining this during the perioperative period.
normothermia
500
This progressive neuromuscular disease, aka Kennedy's Dz, results in degeneration of lower motor neurons --> muscle weakness, atrophy, and fasciculations in affected males. Affected individuals often show gynecomastia, testicular atrophy, and reduced fertility as a result of mild androgen insensitivity
Spinobulbar muscular atrophy
500
The reasons why patients with Myotonic Dystrophy should not be given succinylcholine?
Effect can be unpredictable
- exaggerated contracture and a difficult to ventilate and difficult to intubate scenario.
- hyperkalemia
500
These are the 5 RFs for postoperative ventilation in a pt with MG
-Dz duration>6 yrs
-Concomitant pulmonary dz
-VC< 4cc/kg
-Pyridostigmine dose >750mg/d\
-PIP<-25cm H2O