The Basics
Feelings & Functions
Disorders & Imbalances
Drugs & Effects
Brain Connections
100

Neurotransmitters are chemicals that transmit signals between these cells.

What are neurons?

100

This neurotransmitter helps regulate mood, appetite, and sleep.

What is serotonin?

100

Low levels of serotonin are commonly linked with this mental health disorder.

What is depression?

100

This type of drug increases neurotransmitter activity.

What is an agonist?

100

Dopamine is released heavily in this brain system associated with reward and addiction.

What is the limbic system (or reward pathway/mesolimbic pathway)?

200

This small gap between neurons is where neurotransmitters travel.

What is the synaptic cleft (or synapse)?

200

These “feel-good” neurotransmitters act as natural painkillers.

What are endorphins?

200

Excess dopamine activity is associated with this serious mental disorder.

What is schizophrenia?

200

This type of drug decreases or blocks neurotransmitter activity.

What is an antagonist?

200

Acetylcholine plays a major role in this brain region involved in learning and memory.

What is the hippocampus?

300

This neurotransmitter is most associated with pleasure, reward, and motivation.

What is dopamine?

300

This neurotransmitter prepares the body for fight-or-flight responses.

What is adrenaline (epinephrine)?

300

A lack of acetylcholine is linked to this neurodegenerative disorder that affects memory.

What is Alzheimer’s disease?

300

SSRIs (selective serotonin reuptake inhibitors) increase levels of this neurotransmitter.

What is serotonin?

300

GABA and glutamate work together to maintain this balance in brain activity.

What is excitation–inhibition balance?

400

This neurotransmitter enables muscle movement and is linked to learning and memory.

What is acetylcholine (ACh)?

400

The neurotransmitter that boosts alertness and arousal but is not purely excitatory.

What is noradrenaline (norepinephrine)?

400

Low levels of GABA are linked to this condition involving extreme nervousness or tension.

What is anxiety?

400

Drugs like heroin or morphine mimic this type of neurotransmitter.

What are endorphins?

400

DAILY DOUBLE: Noradrenaline and adrenaline are produced in this part of the brainstem that controls alertness.

What is the locus coeruleus (or adrenal medulla for adrenaline)?

500

This neurotransmitter is the brain’s main inhibitory neurotransmitter.

What is GABA (gamma-aminobutyric acid)?

500

This excitatory neurotransmitter strengthens neural connections and is vital for learning and memory.

What is glutamate?

500

Overactivation of glutamate can lead to this damaging process that kills neurons.

What is excitotoxicity (or seizures/stroke damage)?

500

Nicotine acts as an agonist for this neurotransmitter that controls muscle movement.

What is acetylcholine?

500

Endorphins are released from this brain region during intense exercise, reducing pain perception.

What is the pituitary gland?

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