Anatomy
Name the Neurotransmitter
Synthesis
Clinical Applications
Elimination
100

Which lobe of the brain is responsible for personality characteristics, decision-making, and motor control?

Frontal Lobe

100

Facilitates muscle contraction, cognition, memory, and autonomic nervous system regulation

Acetylcholine (ACh)

100

Histidine is decarboxylated to become what?

Histamine

100

Which types of drugs are prescribed to people with depression?

SSRIs

100

Which enzyme is responsible for eliminating acetylcholine?

Acetylcholinesterase

200

Which 2 main structures make up the central nervous system?

Brain and Spinal Cord

200

The main excitatory neurotransmitter in the brain.

Glutamate

200

Dopamine, norepinephrine, and epinephrine derive from this amino acid.

Tyrosine

200

If someone is having an allergic reaction and cannot breathe, what treatment is given?

Epi-Pen

200

The most common way serotonin is eliminated.

Re-uptake

300

The myelin sheath, which insulates the axon and causes rapid cell signaling, is made by these cells.

Schwann Cells

300

Inhibitory neurotransmitter that regulates anxiety, sleep, mood, eating, learning, and memory.

Serotonin

300

Which enzyme is responsible for the conversion of norepinephrine to epinephrine?

N-methyl-transferase

300

Excess glutamate in the spinal cord results to this disease.

ALS (Lou Gehrig's Disease)

300

What does "MAO" stand for in the MAO enzyme responsible for breaking down dopamine?

Monoamine Oxidase

400

What 2 parts of the neuron are where repolarization and depolarization occur (if the signal is large enough)?

Axon and Axon Hillock

400

If atropine is a muscarinic antagonist, which neurotransmitter does it act on?

Acetylcholine

400

Which enzyme converts 5-HTP to 5-HT (serotonin)?

Aromatic amino acid decarboxylase

400

Low levels of GABA result in this disease.

Epilepsy

400

These types of drugs inhibit serotonin from avoiding re-uptake so it stays longer in the synapse to bind to receptors to activate it.

SSRIs

500

This calcium sensor protein regulates the flow of transmission by opening/fusing vesicles to allow the release of neurotransmitters across the synaptic cleft.

Synaptotagmin

500

Caffeine decreases levels of which neurotransmitter in the synapse?

GABA

500

Which vitamin acts as a coenzyme of GAD in order to decarboxylate glutamate?

PLP

500

Why is L-Dopa given as a treatment to Parkinson's Disease, rather than pure dopamine?

Dopamine cannot pass through the BBB, but L-Dopa can. L-Dopa is the precursor to dopamine, so it can pass through the BBB and be decarboxylated to become dopamine.

500

This treatment inhibits the enzyme that breaks down acetylcholine in Alzheimer's Disease.

Acetylcholinesterase inhibitor

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