Gut and Nutrition
Derm
Equations
Genetics
Lung
Cardiology
Potpourri
In the Lou
100
These fat soluble vitamins are present in low quantities in human milk.
What are Vitamins D and K?
100
Name the condition
What is Harlequin syndrome?
100
A study of 100 babies has a Type 1 error of 0.05 and a Type 2 error of 0.20. The study has this power.
What is 0.8?
100
Name the diagnosis.
What is Monosomy X /
Turner Syndrome?
100
Name the 5 stages of lung development (in order)
Embryonic
Pseudoglandular
Canalicular
Saccular
Alveolar
100
Term infant infant born to a 22 yo G1 mother. RN notes HR 75. Sats 98%. No respiratory distress. EKG shows this.
Identify the diagnosis.
Identify the cause / mechanism.
Describe the prognosis.
What is Complete heart block?
What is neonatal lupus? What are SSA/Ro and SSB/La antibodies?
–Present in 0.1-1.5% healthy women, 90% Sjogren, 20-30% SLE
–80-95% of severe heart block in the neonatal period
–7-16% of infants with seropositive moms have skin manifestations
What are irreversible changes to the conducting system?
100
This tumor is common in children with posterior auricular pits, omphalocele, ear lobe creases, macroglossia, and hypoglycemia.
What is Wilms tumor.
100
The city of St. Louis is named after this person
Who is King Louis IX of France?
St. Louis was named by French fur traders de St. Maxent, Choteau and Laclede, all from New Orleans.
200
The most common maternal condition associated with small left colon syndrome.
What is maternal diabetes?
200
Name this and the most common genetic syndrome associated with this exam finding.
What is cutis aplasia?
What is Trisomy 13?
200
Calculate the Odds Ratio of ROP between those who did and did not receive O2.
What is 0.84?
(a/c) / (b/d)
or, equivalently:
(a*d) / (b*c)
200
Name the genetic condition.
What is Trisomy 18?
200
Name the structure that arises from the foregut and gives rise to the lungs
What is the respiratory diverticulum?
200
A 34 week infant is referred for worsening hypoxia on DOL 3. A radiograph is obtained.
Identify the disease and a treatment to avoid.
What is Total Anomalous Pulmonary Venous Return?
What is inhaled nitric oxide?
200
This eye finding is associated with bile duct paucity with cholestasis, triangular face, and pulmonary valve stenosis.
What is posterior embryotoxin
200
This St. Louis Company was the first to make shoes for different feet: a right shoe and a left shoe
What is the Brown Shoe Company?
300
Describe the caloric density of each component of TPN
What are:
Trophamine = 4 kcal/g
Dextrose = 3.4 kcal/g
Lipid = 9 kcal/g
300
A 28 week infant develops this rash on DOL 3. Name this diagnosis and associated systemic findings.
What is congenital cutaneous candidiasis?
What are thrombocytopenia and hyperglycemia?
300
The equation for fractional excretion of sodium.
What is
("Urine sodium" // "serum sodium") / ("urine creatinine" // "serum creatinine")
-or-
("Urine sodium" xx "serum creatinine" ) / ("urine creatinine" xx "serum sodium")
300
Name the diagnosis and the gene.
What are Cornelia de Lange and NIPBL?
300
Name the stage of lung development where TE fistulas arise.
Name the least common type of TEF.
What is the Embryonic stage?
What is B-type TEF?
Clements BS. Congenital malformations of the lung and airways. In: Pediatric Respiratory Medicine, 1st ed, Taussig LM, Landau LI (Eds), Mosby, St. Louis 1999. Vol 1, p.1115
300
A fetus has a ventricular rate of 120 with an atrial rate of 240.
This describes his arrhythmia, conduction pattern, therapy and likely neonatal course.
What is atrial flutter with 2:1 block, synchronized cardioversion with no recurrence.
Initial EKG:
With adenosine push:
300
This condition includes craniosynostosis, hypertelorism single nails, broad thumbs, and syndactyly.
What is Apert syndrome?
300
Name these 3 St. Louis landmarks/businesses
St. Louis Bread Company
Ted Drewe's
Crown Candy Kitchen
400
Soy formula is not recommended in the preterm population due to this risk.
What is osteopenia?
400
Name this condition and the first-line treatment.
What is staphylococcal scalded skin syndrome?
What is oxacillin?
400
The formula to calculate the A-a gradient
What is
(P_"atm" - 47 mmHg)*FiO2 - ("PaCO2"/"RQ")
- PaO2
400
Name the diagnosis and associated gene.
What is Neonatal Marfan’s Syndrome and FBN1?
400
FGF10 binds to FGFR2 receptor to initiate lung bud formation and is essential for branching.
Mutations in FGFR2 result in these genetic syndromes.
What are Apert, Pfeifer, Crouzon syndromes?
400
A term infant is cyanotic with saturations in the 70% despite intubation and 100% FiO2. This radiograph is obtained.
Name the diagnosis and a possible complicating circulation pattern.
What is Ebstein's anomaly?
What is a circular shunt?
400
This metabolic disease can cause subdural hematomas and retinal hemorrhages, which have be mistaken for child abuse.
What is Glutaric aciduria type 1?
400
What type of arch is the St. Louis Arch?
Bonus points: How tall is the St. Louis arch?
Catenary Arch
630 feet
500
A 500 gram 23 week infant at 36 hours of age has a Na of 155. UOP is 7 mL/kg/hr. In addition to maintenance fluids, you prescribe this much free water over the next 24 hours with a goal Na of this.
"Free water deficit" = "total body water" xx (Na_"now" - Na_"goal") / (Na_"goal")
TBW = "body water percent" xx weight
"Free water deficit" = "0.85" xx "0.5 kg" xx (155-145) / 145 = "29 mL"
"What is 145?"
500
Name the condition and associated cardiac findings.
What is congenital rubella syndrome?
What are PPS and PDA?
500
The NEC rate in your unit is 3%. A drug rep claims their prebiotic reduces NEC to 50% of their previous rates.
You need to treat this many patients to see one less case of NEC.
What is 67 patients?
"RRR" = "1.5%"/"3%" = 0.5
"ARR" = "3%"-"1.5%" = "1.5%"
"NNT" = 1/"ARR"
500
Name the diagnosis.
Name 1 of the associated genes.
What is Treacher Collins?
What are POLR1C, POLR1D, TCOF1?
500
1) The image on the right from a lung barium angiogram is illustrating this rare neonatal lung disease.
2) This gene is typically disrupted in this disorder.
What is Alveolar capillary dysplasia?
What is FOXF1?
500
Calculate the mL of oxygen per dL blood in a 1.4 kg 30 week infant with a Hgb of 9.2 g/dL, PaO2 70, SpO2 92%.
What is 1.34 mL O2 / g Hgb x 9.2 g/dL x 92% + 0.003 x 70
= 11.6 mL O2 per dL blood
500
This term infant is referred for feeding issues and drooling on DOL 1.
What is Smith–Lemli–Opitz syndrome (SLOS) ?
- autosomal recessive, intellectual disability syndrome,
What is DHCR7?
- reduces or eliminates the activity of 7-dehydrocholesterol reductase, preventing cells from producing enough cholesterol
500
Which family member of Taylor's attended college in the St. Louis area? Which school did they attend?
Taylor's grandmother Marjorie Moehlenkamp Finlay attended Lindenwood College in St. Charles, MO
She graduated in 1949 with a Bachelor of Music in Voice. Taylor references her love for her grandmother in "Marjorie" from the Evermore album.